{"id":10389,"date":"2022-02-21T12:00:00","date_gmt":"2022-02-21T03:00:00","guid":{"rendered":"https:\/\/symdfmtcopro.wpenginepowered.com\/post\/10389"},"modified":"2025-03-24T23:14:33","modified_gmt":"2025-03-24T14:14:33","slug":"autism-spectrum-disorder-and-other-disorders-in-a-female-in-her-40s-fecal-microbiota-transplantation-case-report","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/10389","title":{"rendered":"Autism Spectrum Disorder and Other Disorders in a Female in her 40s &#8211; Fecal Microbiota Transplantation Case Report"},"content":{"rendered":"<h2><span class=\"ez-toc-section\" id=\"i\"><\/span>Case presentation Female in her 40s, autistic spectrum disorder, other disorders<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"i-2\"><\/span>summary<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div>\n<div>HSP, ADHD tendencies. Hypersensitive and fearful since childhood. As an adult, had mood swings and had difficulty living.<br \/>After the first transplant, her anxiety and other feelings disappeared.<\/div>\n<\/div>\n<div><div class=\"su-table su-table-responsive su-table-fixed\"><\/div>\n<h3><span class=\"ez-toc-section\" id=\"i-3\"><\/span>Basic Information<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 50%\">Patients :<\/td>\n<td style=\"width: 50%\">Woman in her 40s<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Attending physician :<\/td>\n<td style=\"width: 50%\"><a href=\"https:\/\/naturalartclinic.com\/\" target=\"_blank\" rel=\"noopener\">Natural Art Clinic<i class=\"icon-new-tab\"><\/i><\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%\">Medical institution in charge of transplantation :<\/td>\n<td style=\"width: 50%\"><a href=\"https:\/\/naturalartclinic.com\/\" target=\"_blank\" rel=\"noopener\">Natural Art Clinic<i class=\"icon-new-tab\"><\/i><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<h3><span class=\"ez-toc-section\" id=\"i-4\"><\/span>Information at the time of initial medical examination<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table style=\"width: 100%;height: 175px\">\n<tbody>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Disease name :<\/td>\n<td style=\"height: 25px\">Autism Spectrum Disorders, Other Disorders<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">At onset :<\/td>\n<td style=\"height: 25px\">Since as far back as I can remember. Diagnosed in 2016.<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Transplant Purpose: To<\/td>\n<td style=\"height: 25px\">Improvement of symptoms such as irritability, tantrums, tiredness, diarrhea, gas, etc.<br \/>Skin problems (including atopic dermatitis), constitutional improvement<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Chief complaint :<\/td>\n<td style=\"height: 25px\">\n<div>Although I was diagnosed only as an adult, I have always had elements of social anxiety disorder since childhood. I feel fear and anxiety about everything I don&#8217;t understand and get extremely nervous when I go out in public.<br \/>She had HSP (HSS) and often felt uncomfortable with various stimuli and information in his daily life, making it difficult for him to live.<\/div>\n<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Medications being taken :<\/td>\n<td style=\"height: 25px\">\u00a0<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Medical history :<\/td>\n<td style=\"height: 25px\">\u00a0<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Background, family history, lifestyle, supplement use, etc :<\/td>\n<td style=\"height: 25px\">\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<h3><span class=\"ez-toc-section\" id=\"i-5\"><\/span>Transplant Information<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td>Transplantation period: from<\/td>\n<td>July 16, 2021 &#8211; August 17, 2021<\/td>\n<\/tr>\n<tr>\n<td>Number of transplants :<\/td>\n<td>6 times<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>Change from first transplant to end of transplant :<\/td>\n<\/tr>\n<tr>\n<td>\n<p>\u30101st transplantation questionnaire\u3011<br \/>My physical condition has not changed. Her stomach is not bad, but her stools are always loose.<br \/>Dietary guidance was also given.<br \/>(1) Drink at least 2 liters of water, (2) consume soluble fiber and root vegetables, (3) no glycene, and (4) no casein.<\/p>\n<p>\u30102nd transplantation questionnaire\u3011<br \/>After the transplant, I felt less anxious and fidgety.<br \/>Before, when she tried to work, she used to produce anxious substances, but they disappeared and she was able to start work more easily.<br \/>No change in sleep quality.<br \/>There was a positive change in her mental health, so we will continue to monitor changes.<\/p>\n<p>\u30103rd transplantation questionnaire\u3011<br \/>The diarrhea was getting better.<br \/>Mental condition is also calming down.<br \/>She is consciously taking root vegetables such as carrots, onions, pumpkin, and sweet potatoes.<br \/>Last time, there was abdominal bloating for about 2 hours after transplant.<br \/>There are many positive changes, and we will continue to monitor her progress.<\/p>\n<p>\u30104th transplantation questionnaire\u3011<br \/>Feeling good physically. Mental stability.<br \/>Soft stools used to occur 3-4 times a day, but decreased to 1-2 times a day, and now basically normal stools.<\/p>\n<p>\u30105th transplantation questionnaire\u3011<br \/>I had the best feeling at the first time. I felt good after that.<br \/>Mental and bowel movements stable.<br \/>I have a feeling of stomach acidity around 2 hours after taking protein in the morning. No hunger.<br \/>Will be adding a banana to breakfast to help with serotonin.<\/p>\n<p>\u30106th transplantation questionnaire\u3011<br \/>I&#8217;m feeling good.<br \/>Mental and bowel movements are both good. Sleep is good.<br \/>Diet has changed a lot since the transplant.<br \/>(Increased root vegetables and no longer consuming wheat. Started adding 2\/3 brown rice to white rice. Oatmeal is consumed occasionally).<\/p>\n<p>\u3010Questionnaire at the 2 month post-inspection\u3011<br \/>I&#8217;m feeling good.<br \/>I feel that the results are quite good, with the target balance of bacteria almost reached.<br \/>I will pay attention to my diet and continue to monitor the progress.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"i-6\"><\/span>Intestinal flora balance Comparative data<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"613\" src=\"https:\/\/fmt-japan.org\/wp-content\/uploads\/2022\/01\/e2eca5b5f4a60052f1ab1577f2b0ac61-1024x613.jpg\" alt=\"\" class=\"wp-image-7137\" srcset=\"https:\/\/fmt-japan.org\/wp-content\/uploads\/2022\/01\/e2eca5b5f4a60052f1ab1577f2b0ac61-1024x613.jpg 1024w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2022\/01\/e2eca5b5f4a60052f1ab1577f2b0ac61-300x179.jpg 300w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2022\/01\/e2eca5b5f4a60052f1ab1577f2b0ac61-768x459.jpg 768w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2022\/01\/e2eca5b5f4a60052f1ab1577f2b0ac61-1536x919.jpg 1536w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2022\/01\/e2eca5b5f4a60052f1ab1577f2b0ac61.jpg 1852w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n<table style=\"width: 100%\">\n<tbody>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px;width: 30%\">Blood test changes :<\/td>\n<td style=\"height: 25px;width: 70%\">Not implemented<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px;width: 30%\">CHANGE IN POMS2 SCORE :<\/td>\n<td style=\"height: 25px;width: 70%\">Not implemented<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>His\/her experience (from the questionnaire) :<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h3><span class=\"ez-toc-section\" id=\"i-7\"><\/span>Evaluation and Discussion<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"height: 25px;width: 30%\">Transplant Evaluation :<\/td>\n<td style=\"height: 25px;width: 70%\">Clear improvement of symptoms<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 100%\">\n<tbody>\n<tr>\n<td style=\"height: 25px;width: 30%\">Adverse events: No<\/td>\n<td style=\"height: 25px;width: 70%\">Nothing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>Changes after completion of transplant :<\/td>\n<\/tr>\n<tr>\n<td>Anxiety disappeared after the first transplant. Stools also improved.<br \/>Felt the best after the first transplant, but maintained good condition after that.<br \/>No longer anxious or irritable.<br \/>Her diet has also changed significantly from before the transplant.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table style=\"font-size: 1rem\">\n<tbody>\n<tr>\n<td>Transplant General Comments and Discussion :<\/td>\n<\/tr>\n<tr>\n<td>As mentioned above, the effects were felt from after the first transplant.<br \/>Anxiety decreased, and subsequently, impatience and irritability also disappeared. Normalization of stools also normalized.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>&#8230; and upwards<\/p>\n<hr>\n<p><a href=\"https:\/\/fmt-japan.org\/category\/fmt_cases\">Return to Top of Case Studies<i class=\"icon-new-tab\"><\/i><\/a><\/p>","protected":false},"excerpt":{"rendered":"Case presentation Female in her 40s, autistic spectrum disorder, other disorders summary HSP, ADHD tendencies. Hypersensitive and fearful since childhood. As an adult, had mood swings and had difficulty living.After the first transplant, her anxiety and other feelings disappeared. Evaluation and Discussion &#8230; and upwards Return to Top of Case Studies","protected":false},"author":1,"featured_media":10391,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[109,101],"tags":[141,112,126],"class_list":["post-10389","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fmt_cases","category-study","tag-asd","tag-futamatakai-medical-corporation-natural-art-clinic","tag-other-diseases"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Autism Spectrum Disorder and Other Disorders in a Female in her 40s - Fecal Microbiota Transplantation Case Report - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fmt-japan.org\/post\/7136\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Autism Spectrum Disorder and Other Disorders in a Female in her 40s - Fecal Microbiota Transplantation Case Report - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a\" \/>\n<meta property=\"og:description\" content=\"Case presentation Female in her 40s, autistic spectrum disorder, other disorders summary HSP, ADHD tendencies. 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Hypersensitive and fearful since childhood. As an adult, had mood swings and had difficulty living.After the first transplant, her anxiety and other feelings disappeared. 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