{"id":10414,"date":"2020-06-26T16:01:39","date_gmt":"2020-06-26T07:01:39","guid":{"rendered":"https:\/\/symdfmtcopro.wpenginepowered.com\/post\/10414"},"modified":"2023-10-24T16:49:24","modified_gmt":"2023-10-24T07:49:24","slug":"allergic-pollinosis-male-in-his-30s-case-report-of-fecal-microflora-transplantation","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/10414","title":{"rendered":"Allergic pollinosis, male in his 30s -Case report of fecal microflora transplantation"},"content":{"rendered":"<h2><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"i\"><\/span>summary<span class=\"ez-toc-section-end\"><\/span><\/h3>\nShe applied for transplantation to improve her hay fever symptoms, which began 10 years ago and have been worsening for the past 7 years. Transplantation was performed 3 times on 23.12.2019, 25.12.2019 and 10.1.2020. The patient returned to the hospital 2 weeks after the transplantation. She has already experienced hay fever symptoms, and no change from previous years, so she does not feel any effect so far.\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<h3><span class=\"ez-toc-section\" id=\"i-2\"><\/span>Basic Information<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td>Patients :<\/td>\n<td>30&#8217;s Male<\/td>\n<\/tr>\n<tr>\n<td>Attending physician :<\/td>\n<td><a href=\"http:\/\/sante-clinic.jp\/\" target=\"_blank\" rel=\"noopener noreferrer\">Medical Corporation Sakurashinkai Sante Clinic<i class=\"icon-new-tab\"><\/i><\/a><\/td>\n<\/tr>\n<tr>\n<td>Medical institution in charge of transplantation :<\/td>\n<td><a href=\"http:\/\/sante-clinic.jp\/\" target=\"_blank\" rel=\"noopener noreferrer\">Medical Corporation Sakurashinkai Sante Clinic<i class=\"icon-new-tab\"><\/i><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<h3><span class=\"ez-toc-section\" id=\"i-3\"><\/span>Information at the time of initial medical examination<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table style=\"width: 49.3525%;height: 175px\">\n<tbody>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Disease name :<\/td>\n<td style=\"height: 25px\">Allergy\/Hay fever<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">At onset :<\/td>\n<td style=\"height: 25px\">About 10 years ago<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Transplant Purpose: To<\/td>\n<td style=\"height: 25px\">Improvement of symptoms described in the disease<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Chief complaint :<\/td>\n<td style=\"height: 25px\">He has been suffering from hay fever for 10 years. 7 years ago, his symptoms started to worsen. 2016-2018, sublingual immunotherapy was performed but there was no improvement. Recently, she evacuates to Okinawa and other places during hay fever season. Symptoms are mainly pharyngeal and ocular symptoms. Rhinitis symptoms are weak.<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Medications being taken :<\/td>\n<td style=\"height: 25px\">Antiallergic (details unknown)<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Medical history :<\/td>\n<td style=\"height: 25px\">Appendicitis at age 10.<\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px\">Background, family history, lifestyle, supplement use, etc :<\/td>\n<td style=\"height: 25px\">Lactobacillus supplements<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<h3><span class=\"ez-toc-section\" id=\"i-4\"><\/span>Transplant Information<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table>\n<tbody>\n<tr>\n<td>Transplantation period: from<\/td>\n<td>December 23, 2019 &#8211; January 10, 2020<\/td>\n<\/tr>\n<tr>\n<td>Number of transplants :<\/td>\n<td>3 times<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>Change from first transplant to end of transplant :<\/td>\n<\/tr>\n<tr>\n<td>\n\u30101st transplantation questionnaire\u3011\nNo abdominal symptoms.\n\u30102nd transplantation questionnaire\u3011\nNo abdominal symptoms, no trouble Immediately\nafter the last transplant, I had loose stools, but after that, I had normal hard stools 2 to 3 times a day yesterday and today. I take care of my sleep and exercise.\n\u30103rd transplantation questionnaire\u3011\nNo abdominal symptoms No trouble\nNo change in symptoms<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>Changes after completion of transplant :<\/td>\n<\/tr>\n<tr>\n<td>Now following<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<h3><span class=\"ez-toc-section\" id=\"i-5\"><\/span>Evaluation and Discussion<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<table style=\"width: 100%;height: 409px\">\n<tbody>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px;width: 16.7763%\">Transplant Evaluation :<\/td>\n<td style=\"height: 25px;width: 83.114%\">None in particular.<\/td>\n<\/tr>\n<tr style=\"height: 48px\">\n<td style=\"height: 48px;width: 16.7763%\">Pre- and post-transplant flora balance test changes :<\/td>\n<td style=\"height: 48px;width: 83.114%\">\n<div>A larger percentage cannot be classified as Other, and the diversity of intestinal flora is low.<\/div>\n<div>The ideal ratio of C-cluster IX to C-cluster XIVab is 1:4 from a mental point of view, but the ratio of XIVab is higher at 1:9.<\/div>\n<div>The detection of Equol-producing bacteria (tissue regeneration), C cluster 11, and XV (inflammatory response) suggests acute inflammation, and the percentage of C cluster XIVab may be high to maintain that immune tolerance state.<\/div>\n<div>Also, I understand that you have had appendicitis.<\/div>\n<div>The appendix is the organ responsible for intestinal immunity (IgA) and affects the bacterial flora balance. Damage to the appendix may result in an inadequate intestinal barrier and cause the preceding inflammation.<\/div>\n<div>Hence, intestinal damage may cause inadequate immune tolerance, which may be the cause of uncontrolled allergic reactions.<\/div><\/td>\n<\/tr>\n<tr style=\"height: 25px\">\n<td style=\"height: 25px;width: 16.7763%\">Blood test changes :<\/td>\n<td style=\"height: 25px;width: 83.114%\">under inspection<\/td>\n<\/tr>\n<tr style=\"height: 48px\">\n<td style=\"height: 48px;width: 16.7763%\">POMS2 SCORE CHANGE :<\/td>\n<td style=\"height: 48px;width: 83.114%\">under inspection<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n\uff1cIntestinal flora balance Relocation\uff1e<img decoding=\"async\" class=\"aligncenter wp-image-5273\" src=\"https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/1591940386435-300x229.jpg\" alt=\"\" width=\"537\" height=\"411\" srcset=\"https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/1591940386435-300x229.jpg 300w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/1591940386435-768x586.jpg 768w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/1591940386435.jpg 962w\" sizes=\"(max-width: 537px) 100vw, 537px\" \/>\n\n\uff1cIntestinal flora balance Post-transplant data\uff1e\n<img decoding=\"async\" class=\"aligncenter wp-image-5274\" src=\"https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/8e1b831cc1b2fb946e6037bc92c623dc-300x240.png\" alt=\"\" width=\"534\" height=\"427\" srcset=\"https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/8e1b831cc1b2fb946e6037bc92c623dc-300x240.png 300w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/8e1b831cc1b2fb946e6037bc92c623dc-768x613.png 768w, https:\/\/fmt-japan.org\/wp-content\/uploads\/2020\/06\/8e1b831cc1b2fb946e6037bc92c623dc.png 954w\" sizes=\"(max-width: 534px) 100vw, 534px\" \/>\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>His\/her experience (from the questionnaire) :<\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-size: inherit\">\nunder request<\/div><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>Adverse events: No<\/td>\n<\/tr>\n<tr>\n<td>Nothing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n<div class=\"su-table su-table-responsive su-table-fixed\">\n<table>\n<tbody>\n<tr>\n<td>Transplant General Comments and Discussion :<\/td>\n<\/tr>\n<tr>\n<td>Symptoms of hay fever have already appeared, and the patient is currently unaware of any changes after transplantation. Since the hay fever season will be in full swing from now on, follow-up observation is necessary to determine changes in symptoms.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n&#8230; and upwards\n\n<hr>\n\n<a href=\"https:\/\/fmt-japan.org\/category\/fmt_cases\">Return to Top of Case Studies<i class=\"icon-new-tab\"><\/i><\/a>","protected":false},"excerpt":{"rendered":"summary She applied for transplantation to improve her hay fever symptoms, which began 10 years ago and have been worsening for the past 7 years. Transplantation was performed 3 times on 23.12.2019, 25.12.2019 and 10.1.2020. The patient returned to the hospital 2 weeks after the transplantation. She has already experienced hay fever symptoms, and no [&hellip;]","protected":false},"author":1,"featured_media":10070,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[109],"tags":[97],"class_list":["post-10414","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fmt_cases","tag-medical-corporation-sakura-shinkai-sante-clinic"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Allergic pollinosis, male in his 30s -Case report of fecal microflora transplantation - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fmt-japan.org\/post\/5223\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Allergic pollinosis, male in his 30s -Case report of fecal microflora transplantation - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a\" \/>\n<meta property=\"og:description\" content=\"summary She applied for transplantation to improve her hay fever symptoms, which began 10 years ago and have been worsening for the past 7 years. 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Transplantation was performed 3 times on 23.12.2019, 25.12.2019 and 10.1.2020. The patient returned to the hospital 2 weeks after the transplantation. 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