{"id":10421,"date":"2020-01-07T10:00:15","date_gmt":"2020-01-07T01:00:15","guid":{"rendered":"https:\/\/symdfmtcopro.wpenginepowered.com\/post\/10421"},"modified":"2023-11-29T19:08:58","modified_gmt":"2023-11-29T10:08:58","slug":"atopic-dermatitis-4-year-old-boy-fecal-microflora-transplantation-case-report","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/10421","title":{"rendered":"Atopic dermatitis, 4-year-old boy -Fecal microflora transplantation case report"},"content":{"rendered":"

<\/span>Case presentation: 4-year-old boy, atopic dermatitis (under observation)<\/span><\/h2>\r\n

<\/span>summary<\/span><\/h3>\r\n

She had food sensitivity and itchy, dry skin all over her body. After the transplant, the itching became worse for a while, but after the sixth and final transplant, the degree of itching improved, and at the time of the eighth transplant, she did not scratch her body at the examination, and the skin rash became less severe.
It is hoped that the restoration of lactobacilli will improve the mitochondrial function by repairing the intestinal wall and improving the intestinal environment, leading to an improvement in hypersensitivity.<\/p>\r\n

\r\n

<\/span>Basic Information<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n\r\n
Patients :<\/td>\r\n4 years old, boy<\/td>\r\n<\/tr>\r\n
Attending physician :<\/td>\r\nHaruna Clinic<\/i><\/a><\/td>\r\n<\/tr>\r\n
Medical institution in charge of transplantation :<\/td>\r\nHaruna Clinic<\/i><\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n

<\/span>Information at the time of initial medical examination<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n
Disease name :<\/td>\r\nAtopic dermatitis, food sensitivities<\/td>\r\n<\/tr>\r\n
Time of onset :<\/td>\r\n0 year old<\/td>\r\n<\/tr>\r\n
Transplant Purpose: To<\/td>\r\nAllergies (target; most foods)
skin problem
Other (atopic dermatitis, food sensitivities)<\/td>\r\n<\/tr>\r\n
Chief complaint :<\/td>\r\nEczema, itching, food sensitivities<\/td>\r\n<\/tr>\r\n
Medications being taken :<\/td>\r\nNothing<\/td>\r\n<\/tr>\r\n
Medical history :<\/td>\r\nepilepsy<\/td>\r\n<\/tr>\r\n
Background, family history, lifestyle, supplement use, etc :<\/td>\r\nALVEX, LACTIC ACID BACTERIA, VITAMIN D<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n

<\/span>Transplant Information<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n
Transplantation period: from<\/td>\r\nMay 25, 2019 – September 28, 2019<\/td>\r\n<\/tr>\r\n
Number of transplants :<\/td>\r\n8 times<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n\r\n\r\n\r\n\r\n
Change from first transplant to end of transplant :<\/td>\r\n<\/tr>\r\n
\r\n

There was no change until the 6th session, but after the 7th session, the skin peeled off and the itching calmed down somewhat. However, the food sensitivity has not changed.<\/p>\r\n

\u30101st transplantation questionnaire\u3011
Atopic eczema and itching all over her body, but she is in a good mood.
I hope that the sensitivity will be removed by transplantation.
\u30102nd transplantation questionnaire\u3011
Itching became stronger for 2 days from the day after transplant and she could not sleep.
The color and hardness of his stools are improving.
\u30103rd transplantation questionnaire\u3011
Itching has become severe and she sometimes has trouble sleeping due to itching.
The skin is scattered with erythema all over.
\u30104th transplantation questionnaire\u3011
Itching and skin condition remain the same.
\u30105th transplantation questionnaire\u3011
He was constantly scratching himself during the examination, although it is getting better little by little.
\u30106th transplantation questionnaire\u3011
The condition of the skin remains the same, with scattered dry skin rashes. He was constantly scratching his face and head.
The patient’s irritability has not changed, but she feels that it is getting worse and worse.
\u30107th transplantation questionnaire\u3011
Shortly after the 6th transplant, she had a severe gastrointestinal cold.
The skin condition improved a little, but the intestinal sensitivity remained the same.
The itchiness improved a little and he was able to sleep.
\u30108th transplantation questionnaire\u3011
The degree of itching has improved.
The dryness of the skin has also improved, and the number of clean areas has increased.
However, he is still applying steroids.<\/p>\r\n<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>

\r\n\r\n\r\n\r\n\r\n
Changes after completion of transplant :<\/td>\r\n<\/tr>\r\n
Slightly more itchy<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n

<\/span>Evaluation and Discussion<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n\r\n\r\n
Transplant Evaluation :<\/td>\r\nMild improvement of symptoms<\/td>\r\n<\/tr>\r\n
Pre- and post-transplant flora balance test changes :<\/td>\r\nawaiting test results<\/td>\r\n<\/tr>\r\n
Blood test changes :<\/td>\r\n\r\n

Eosinophils and IgE are increasing
Zinc and copper are becoming more balanced<\/span><\/p>\r\n<\/td>\r\n<\/tr>\r\n

POMS2 SCORE CHANGE :<\/td>\r\nNot implemented<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n

\uff1cIntestinal flora balance before transplant data\uff1e
\"\"<\/p>\r\n

\uff1cIntestinal flora balance Post-transplant data\uff1e<\/p>\r\n

awaiting results<\/p>\r\n<\/p>\r\n

\r\n\r\n\r\n\r\n\r\n
His\/her experience (from the questionnaire) :<\/td>\r\n<\/tr>\r\n
I didn’t really feel better, but after the 7th transplant, the itching seemed to be a little less. Food sensitivity has not changed.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n\r\n\r\n\r\n\r\n
Adverse events: No<\/td>\r\n<\/tr>\r\n
Nothing<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n\r\n\r\n\r\n\r\n
Transplant General Comments and Discussion :<\/td>\r\n<\/tr>\r\n
The transplant has gradually improved the degree of atopy, but food sensitivities have not changed. He is considering additional transplants in the future while growing the transplanted fungal solution.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n

… and upwards<\/p>\r\n

\r\n

Return to Top of Case Studies<\/i><\/a><\/p>\r\n\r\n

<\/p>\r\n","protected":false},"excerpt":{"rendered":"Case presentation: 4-year-old boy, atopic dermatitis (under observation) summary She had food sensitivity and itchy, dry skin all over her body. 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