{"id":10423,"date":"2020-01-06T14:00:22","date_gmt":"2020-01-06T05:00:22","guid":{"rendered":"https:\/\/symdfmtcopro.wpenginepowered.com\/post\/10423"},"modified":"2023-11-29T19:16:50","modified_gmt":"2023-11-29T10:16:50","slug":"dysautonomia-and-adrenal-fatigue-syndrome-female-in-her-40s-fecal-microflora-transplantation-case-report","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/10423","title":{"rendered":"Dysautonomia and Adrenal Fatigue Syndrome, Female in her 40s -Fecal Microflora Transplantation Case Report"},"content":{"rendered":"

<\/span>Case presentation: Female in her 40s,  depression tendency<\/span><\/h2>\r\n

<\/span>summary<\/span><\/h3>\r\n

Since meniscus knee surgery in September, I have been depressed and feel better in the morning but worse in the afternoon and evening. She feels better at night. Her bowel movements are sluggish with a feeling of residual bowel movements. She has little appetite, especially during menstruation and ovulation. Sleep is shallow, palms are sweaty, and sympathetic nerves are tense.<\/p>\r\n

\r\n

<\/span>Basic Information<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n\r\n
Patients :<\/td>\r\n40s Female<\/td>\r\n<\/tr>\r\n
Attending physician :<\/td>\r\nHaruna Clinic<\/i><\/a><\/td>\r\n<\/tr>\r\n
Medical institution in charge of transplantation :<\/td>\r\nHaruna Clinic<\/i><\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n

<\/span>Information at the time of initial medical examination<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n
Disease name :<\/td>\r\ndepressive tendency<\/td>\r\n<\/tr>\r\n
Time of onset :<\/td>\r\nOctober 2018<\/td>\r\n<\/tr>\r\n
Transplant Purpose: To<\/td>\r\nDepressive symptoms (mood swings)
Fatigue
Sleep disturbances
Loss of appetite<\/td>\r\n<\/tr>\r\n
Chief complaint :<\/td>\r\nDepression-induced mood swings, overstress, fatigue, loss of appetite<\/td>\r\n<\/tr>\r\n
Medications being taken :<\/td>\r\nNothing<\/td>\r\n<\/tr>\r\n
Medical history :<\/td>\r\nSeptember 2018 left knee meniscus surgery<\/td>\r\n<\/tr>\r\n
Background, family history, lifestyle, supplement use, etc :<\/td>\r\nLactobacillus supplement, Ecryol<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n

<\/span>Transplant Information<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n
Transplantation period: from<\/td>\r\nJuly 9, 2019 – July 30, 2019<\/td>\r\n<\/tr>\r\n
Number of transplants :<\/td>\r\n3 times<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n\r\n\r\n\r\n\r\n
Change from first transplant to end of transplant :<\/td>\r\n<\/tr>\r\n
\r\n

After the first session, I started to sleep more deeply and feel a little hungrier. My poor condition has also improved a little. 2nd and 3rd time, I started to have a good appetite and sleep well.<\/p>\r\n

\u30101st transplantation questionnaire\u3011
She feels well in the morning, but becomes fatigued in the afternoon and evening, and then gets better in the evening.
She has bowel movements every day, but there is a lingering sensation of a stool, and she feels her stomach is tight.
\u30102nd transplantation questionnaire\u3011
Emotionally, there is no significant change.
No bacterial fluid after transplant and normal stools the next day.
\u30103rd transplantation questionnaire\u3011
Bowel movements are getting better.
I feel a little better emotionally.
Sleep is getting better.
\u3010Questionnaire 3 months after transplantation\u3011
The change in her mood has lessened since the transplantation, and her appetite has increased.
Sleep is good with a sense of sound sleep.
She is considering what to do about her menstruation and ovulation problems.<\/p>\r\n<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>

\r\n\r\n\r\n\r\n\r\n
Changes after completion of transplant :<\/td>\r\n<\/tr>\r\n
Her appetite has improved and her energy is increasing, though not completely.
She is considering what to do about her menstrual and ovulation problems.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n

<\/span>Evaluation and Discussion<\/span><\/h3>\r\n\r\n\r\n\r\n\r\n\r\n\r\n
Transplant Evaluation :<\/td>\r\nModerate improvement of symptoms<\/td>\r\n<\/tr>\r\n
Pre- and post-transplant flora balance test changes :<\/td>\r\nThere is a decrease in brautia and the inflammatory immune overload is improving. Also, diversity is emerging.
However, the percentage of Clostridium 9 is increasing, and it may be important to observe a little more regarding the mental aspect and stability of the intestinal flora.<\/td>\r\n<\/tr>\r\n
Blood test changes :<\/td>\r\nNo particular change.<\/td>\r\n<\/tr>\r\n
POMS2 SCORE CHANGE :<\/td>\r\nTMD HAS NOT CHANGED MUCH, FROM 50 TO 52, BUT TA HAS IMPROVED FROM 20 TO 15, WHICH SEEMS TO HAVE REDUCED ANXIETY AND OTHER SYMPTOMS.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n

\uff1cIntestinal flora balance before transplant data\uff1e
\"\"<\/p>\r\n

\uff1cIntestinal flora balance Post-transplant data\uff1e<\/p>\r\n

\"\"<\/p>\r\n<\/p>\r\n

\r\n\r\n\r\n\r\n\r\n
His\/her experience (from the questionnaire) :<\/td>\r\n<\/tr>\r\n
Appetite and sleep are better and a little more vibrant.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n\r\n\r\n\r\n\r\n
Adverse events: No<\/td>\r\n<\/tr>\r\n
Nothing<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
\r\n\r\n\r\n\r\n\r\n
Transplant General Comments and Discussion :<\/td>\r\n<\/tr>\r\n
Since the end of the first transplant, his appetite and sleep have improved, and there have been no other changes, so the transplant seems to have had an effect.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n

… and upwards<\/p>\r\n

\r\n

Return to Top of Case Studies<\/i><\/a><\/p>\r\n\r\n

<\/p>\r\n","protected":false},"excerpt":{"rendered":"Case presentation: Female in her 40s,  depression tendency summary Since meniscus knee surgery in September, I have been depressed and feel better in the morning but worse in the afternoon and evening. She feels better at night. Her bowel movements are sluggish with a feeling of residual bowel movements. 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