{"id":10430,"date":"2019-08-05T15:27:50","date_gmt":"2019-08-05T06:27:50","guid":{"rendered":"https:\/\/symdfmtcopro.wpenginepowered.com\/post\/10430"},"modified":"2025-03-24T23:16:31","modified_gmt":"2025-03-24T14:16:31","slug":"parkinsons-disease-male-in-his-70s-ongoing-fecal-microbiota-transplantation-case-report","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/10430","title":{"rendered":"Parkinson’s disease, male in his 70s (ongoing)-Fecal microbiota transplantation case report"},"content":{"rendered":"

<\/span>Case presentation Male in his 70s, Parkinson’s disease (ongoing)<\/span><\/h2>\n

<\/span>summary<\/span><\/h3>\nFirst visit on February 15, 2018. About a year ago, she began to have increased tremor in her limbs, body movements, and inability to get enough sleep at night. The tremor is stronger when he is nervous. She tends to be constipated and has bowel movements with Chinese herbal medicine. (As an interim evaluation)\n\n
\n

<\/span>Basic Information<\/span><\/h3>\n\n\n\n\n\n
Patients:.<\/td>\n70s Male<\/td>\n<\/tr>\n
Attending physician:.<\/td>\nTanaka Clinic<\/i><\/a><\/td>\n<\/tr>\n
Medical institution in charge of transplantation:.<\/td>\nTanaka Clinic<\/i><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n
\n

<\/span>Information at the time of initial medical examination<\/span><\/h3>\n\n\n\n\n\n\n\n\n\n
Disease name:.<\/td>\nOther Diseases<\/td>\n<\/tr>\n
At onset<\/td>\nAround 75 years old<\/td>\n<\/tr>\n
Transplant Purpose: To<\/td>\nSymptom improvement<\/td>\n<\/tr>\n
Chief complaint:.<\/td>\ntrembling or shaking of the limbs<\/td>\n<\/tr>\n
Medications being taken:.<\/td>\nglutathione<\/td>\n<\/tr>\n
Medical history<\/td>\nunknown<\/td>\n<\/tr>\n
Background, family history, lifestyle, supplement use, etc.:.<\/td>\nunknown<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n
\n

<\/span>Transplant Information<\/span><\/h3>\n\n\n\n\n
Transplantation period: from<\/td>\nApril 9, 2018 – June 10, 2019 Ongoing<\/td>\n<\/tr>\n
Number of transplants<\/td>\n17 times<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n
\n\n\n\n\n
Change from first transplant to end of transplant:.<\/td>\n<\/tr>\n
\u30101st transplantation questionnaire\u3011\nPost-transplant posterior tremor has stopped.\nGlutathione infusion, hydrogen infusion, and inhalation will be temporarily discontinued during future transplantation.\n\n
\n\n\u30102nd transplantation questionnaire\u3011\nTremor subsided somewhat and sleep improved.\n\n
\n\n\u30103rd transplantation questionnaire\u3011\nTremor improved further. Bowel movements are the result of the use of Chinese herbal medicine.\n\n
\n\n\u30104th transplantation questionnaire\u3011\nImprovement effect of tremor is maintained. Relies on Chinese herbal medicine for bowel movements.\n\n
\n\n\u30105th transplantation questionnaire\u3011\nImprovement effect of tremor is maintained. Relies on Chinese herbal medicine for bowel movements.\n\n
\n\n\u30106th transplantation questionnaire\u3011\nTremor remains in the right leg. Bowel movements do not improve much.\n\n
\n\n\u30107th transplantation questionnaire\u3011\nImprovement effect of tremor was maintained.\n\n
\n\n\u30108th transplantation questionnaire\u3011\nTremor remains.\n\n
\n\n\u30109th transplantation questionnaire\u3011\nTremor in arms and legs remained.\n\n
\n\n\u301010th transplantation questionnaire\u3011\nTremor in arms and legs remained and became stronger when strained. She had a fall when walking on the stairs.\n\n
\n\n\u301011th transplantation questionnaire\u3011\nTremor remains.\n\n
\n\n\u301012th transplantation questionnaire\u3011\nTremor in arms and legs remained and became stronger during tension.\n\n
\n\n\u301014th transplantation questionnaire\u3011\nPatient has a little residual tremor and is constipated.\n\n
\n\n\u301015th transplantation questionnaire\u3011\nShe still has tremor in her arms and legs, and constipation persists.\n\n
\n\n\u301016th transplantation questionnaire\u3011\nTremor in the hands remains and becomes stronger with tension and fatigue.\n\n
\n\n\u301017th transplantation questionnaire\u3011\nShe had residual tremor in her hands and constipation.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n\n\n\n\n
Changes after completion of transplant:.<\/td>\n<\/tr>\n
Tremors in arms and legs, constipation, and little improvement in physical condition have not been observed. (Progress)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n
\n

<\/span>Evaluation and Discussion<\/span><\/h3>\n\n\n\n\n\n\n
Transplant Evaluation:.<\/td>\nNo change<\/td>\n<\/tr>\n
Pre- and post-transplant flora balance test changes:.<\/td>\n[Before transplant] March 2018.\nThe clostridium is unbalanced, low diversity, and typically stressful. It is speculated that there is some suppressed stimulation of the brain, which may be a counterbalance. I believe that an improvement in the balance will improve symptoms.\n\n
\n\n[During transplantation] June 2018.\nThe balance has improved along with the diversification of the Clostridium genus, which was a problem prior to the transplant, and I believe the balance has acquired mental calm. However, the growth of fungi and viruses may be causing a fungal shift phenomenon, pushing other fungi away on the balance graph. We recommend prescribing antifungal medications or testing for fungi and viruses.<\/td>\n<\/tr>\n
Blood test changes:.<\/td>\n\uff3bAfter transplantation] None<\/td>\n<\/tr>\n
POMS2 SCORE CHANGE:.<\/td>\n\uff3bAfter transplantation] None<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n\uff1cIntestinal flora balance before and after transplantation\uff1e\n\"\"
\n\n\n\n\n
His\/her experience (from the questionnaire):.<\/td>\n<\/tr>\n
None at present<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n
Adverse events: No<\/td>\n<\/tr>\n
Nothing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n
Transplant General Comments and Discussion:.<\/td>\n<\/tr>\n
At the time of the 17th transplant, the tremor of Parkinson’s disease persists, but has somewhat improved and progression has stopped compared to the initial visit. Constipation is similar and he is taking laxatives regularly. Glutathione infusion, hydrogen infusion, and oral Rejuzyn are continued.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\n… and upwards\n\n
\n\nReturn to Top of Case Studies<\/i><\/a>","protected":false},"excerpt":{"rendered":"Case presentation Male in his 70s, Parkinson’s disease (ongoing) summary First visit on February 15, 2018. About a year ago, she began to have increased tremor in her limbs, body movements, and inability to get enough sleep at night. The tremor is stronger when he is nervous. She tends to be constipated and has bowel […]","protected":false},"author":1,"featured_media":10431,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[109],"tags":[86,126],"class_list":["post-10430","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fmt_cases","tag-medical-corporation-jinzenkai-tanaka-clinic","tag-other-diseases"],"acf":[],"yoast_head":"\nParkinson's disease, male in his 70s (ongoing)-Fecal microbiota transplantation case report - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fmt-japan.org\/post\/3593\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Parkinson's disease, male in his 70s (ongoing)-Fecal microbiota transplantation case report - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a\" \/>\n<meta property=\"og:description\" content=\"Case presentation Male in his 70s, Parkinson’s disease (ongoing) summary First visit on February 15, 2018. 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