{"id":12762,"date":"2024-04-08T13:12:30","date_gmt":"2024-04-08T04:12:30","guid":{"rendered":"https:\/\/fmt-japan.org\/post\/12762"},"modified":"2024-11-08T10:47:54","modified_gmt":"2024-11-08T01:47:54","slug":"fecal-microbiota-transplantation-in-a-50-year-old-woman-with-ulcerative-colitis","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/12762","title":{"rendered":"Fecal microbiota transplantation in a 50-year-old woman with ulcerative colitis"},"content":{"rendered":"

<\/span>Introduction of cases 50th generation women Ulcerative colitis<\/span><\/h2>\n

<\/p>\n

<\/p>\n

<\/span>summary<\/span><\/h2>\n
FMT for ulcerative colitis (UC).<\/div>\n
After starting FMT, he developed appendicitis, which was relieved by antibiotics. Thereafter, he had a temporary exacerbation (hemorrhage), but gradually improved, which was considered effective for UC.<\/div>\n

<\/p>\n

<\/p>\n

<\/span>Basic Information<\/span><\/h3>\n

<\/p>\n

<\/p>\n

\n\n\n\n\n\n
Patients :<\/td>\nWoman in her 50s<\/td>\n<\/tr>\n
Attending physician :<\/td>\nLuke’s Ashiya Clinic <\/a><\/td>\n<\/tr>\n
\n

Medical institution in charge of transplantation :<\/p>\n<\/td>\n

Luke’s Ashiya Clinic<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

<\/p>\n

<\/p>\n

<\/span>Information at the time of initial medical examination<\/span><\/h3>\n

<\/p>\n

<\/p>\n

\n\n\n\n\n\n\n\n\n
Disease name :<\/td>\nUlcerative colitis, reactive arthritis<\/td>\n<\/tr>\n
At onset :<\/td>\nSince about 1985<\/td>\n<\/tr>\n
Transplant Purpose: To<\/td>\nImprovement of disease, joint pain, etc.<\/td>\n<\/tr>\n
Chief complaint :<\/td>\nArthralgia, stiffness, myalgia, fever, malaise, lower blood<\/td>\n<\/tr>\n
Medical history :<\/td>\nUnexplained severe abdominal pain and fatigue
fibromyalgia
Difficulty walking, venous malformation<\/td>\n<\/tr>\n
Background, family history, lifestyle, supplement use, etc :<\/td>\nSteroid medication, insomnia medications, etc.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

<\/p>\n

<\/p>\n

<\/span>Transplant Information<\/span><\/h3>\n

<\/p>\n

<\/p>\n

\n\n\n\n\n
Transplantation period: from<\/td>\n2022\/1\/15~2022\/2\/26<\/td>\n<\/tr>\n
Number of transplants :<\/td>\n6 transplants<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

<\/p>\n

<\/p>\n

\n\n\n\n\n
Change from first transplant to end of transplant :<\/td>\n<\/tr>\n
\n

\u30101st transplantation questionnaire\u3011
\uff08From a patient)
Diarrhea 10 times a day for 3 days. Started taking Chinese herbal medicine yesterday and a little improvement. She continues to have abdominal pain and abdominal tightness. She has gas in her abdomen. Feels cold.<\/p>\n

Evaluation after the first transplantation]FMT performed for active UC. Temporary appendicitis accompanied, but improved with antibiotics. There was a temporary exacerbation, but it improved. Lower blood loss improved and bowel movements stabilized.<\/p>\n

\u30102nd transplantation questionnaire\u3011
Right lower abdominal pain, improved by reverse abdominal breathing. They are experiencing the effect on transplantation. Anal herpes (vaccinated) with tenderness and small blisters. \u2192Ointment and oral prescription for observation.
(From a patient)
Lighter in both mind and body. Less abdominal tightness and gas since transplant. I was sleepy for a few days after the transplant. I was able to sleep comfortably.<\/p>\n

Right lower abdomen, pain during defecation.<\/p>\n

\u30103rd transplantation questionnaire\u3011
There is a smile. They seem surprised at the change. They seem to be experiencing the effects of the transplant.
(From a patient)
My mind and body felt lighter. I could drive to the clinic alone.<\/p>\n

\u30104th transplantation questionnaire\u3011
Abdominal turgor is mild and no gas. Prescribed Pulsenide for an intermittent use due to constipation tendency after transplantation.
(From a patient)
The day after the last transplant, there was pain in the appendix. He was prescribed antibiotics and transported by ambulance. Hospitalized for 3 days for chronic appendicitis.
CT abdomen with swelling. Symptoms calmed down and the patient was given a 4-day course of antibiotics. Tendency to constipation and headaches since transplant. Magnesium oxide taken internally, but defecation once every 4 days Bristol Scale Type 5-6 Little or no blood loss, but a little pink. Sleep better than before.<\/p>\n

\u30105th transplantation questionnaire\u3011
There is an indication that they are feeling the effects of the transplantation. Bowel movements need to be adjusted and will be adjusted by the family doctor.<\/p>\n

(From a patient)
Stools do not come out clearly. Partial bleeding. A little abdominal tightness, but no pain in the appendicular area. When abdominal symptoms settled down, body aches started to appear. Family members say he is really feeling better. He is able to walk from the parking lot.<\/p>\n

\u30106th transplantation questionnaire\u3011
(From a patient)
Continuous bleeding. He tended to be constipated and also took laxatives (Daiken-chu-tang and sennoside). \uff08He was dizzy yesterday under the influence of these drugs. There is concern about control of bowel movements and continuation of lower blood loss. She is laughing. No longer concerned about small things.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

<\/p>\n

<\/p>\n

\u00a0<\/p>\n

<\/p>\n

<\/p>\n

<\/span>Intestinal flora balance Comparative data<\/span><\/h3>\n

<\/p>\n

<\/p>\n

<\/p>\n

<\/p>\n

<\/p>\n\n\n

\"\"<\/figure>\n\n\n

<\/span>Evaluation and Discussion<\/span><\/h3>\n

<\/p>\n

<\/p>\n

\n\n\n\n\n
Transplant Evaluation :<\/td>\nModerate improvement of symptoms<\/td>\n<\/tr>\n
Adverse events: No<\/td>\nNothing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

<\/p>\n

<\/p>\n

\u00a0<\/p>\n

<\/p>\n

<\/p>\n

\n\n\n\n\n
Transplant Evaluation :<\/td>\n<\/tr>\n
\n
FMT performed for active UC. Temporary appendicitis accompanied, but improved with antibiotics. There was a temporary exacerbation, but it improved. At the 6-month follow-up, her flora was also improved, her symptoms tended to improve, and her quality of life improved. Mentally stable. Because her bowel movements were stable, rectal injection was discontinued.<\/span> She continues to take immunosuppressive drugs and steroids, but the dosage can be reduced compared to that before FMT.<\/span><\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

<\/p>\n

<\/p>\n

\u00a0<\/p>\n

<\/p>\n

<\/p>\n

… and upwards<\/p>","protected":false},"excerpt":{"rendered":"Introduction of cases 50th generation women Ulcerative colitis summary FMT for ulcerative colitis (UC). After starting FMT, he developed appendicitis, which was relieved by antibiotics. Thereafter, he had a temporary exacerbation (hemorrhage), but gradually improved, which was considered effective for UC. Basic Information Patients : Woman in her 50s Attending physician : Luke’s Ashiya Clinic […]","protected":false},"author":1,"featured_media":14158,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[109],"tags":[88,111],"class_list":["post-12762","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fmt_cases","tag-lukes-ashiya-clinic","tag-ulcerative-colitis"],"acf":[],"yoast_head":"\nFecal microbiota transplantation in a 50-year-old woman with ulcerative colitis - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fmt-japan.org\/en\/post\/12762\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fecal microbiota transplantation in a 50-year-old woman with ulcerative colitis - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a\" \/>\n<meta property=\"og:description\" content=\"Introduction of cases 50th generation women Ulcerative colitis summary FMT for ulcerative colitis (UC). After starting FMT, he developed appendicitis, which was relieved by antibiotics. Thereafter, he had a temporary exacerbation (hemorrhage), but gradually improved, which was considered effective for UC. 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