{"id":14146,"date":"2024-11-02T15:36:06","date_gmt":"2024-11-02T06:36:06","guid":{"rendered":"https:\/\/fmt-japan.org\/?p=14146"},"modified":"2024-11-02T15:36:31","modified_gmt":"2024-11-02T06:36:31","slug":"r01117-12-year-old-girl-with-autism-spectrum-disorder-fecal-microbiota-transplant-case-report","status":"publish","type":"post","link":"https:\/\/fmt-japan.org\/en\/post\/14146","title":{"rendered":"12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report"},"content":{"rendered":"\n

<\/span>Case presentation 12-year-old girl with autistic spectrum disorder<\/span><\/h2>\n\n

<\/span>summary<\/span><\/h2>\n\n

A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity.<\/p>\n\n

<\/span>Basic Information<\/span><\/h3>\n\n
Patients :<\/td>12-year-old girl<\/td><\/tr>
Attending physician :<\/td>Luke’s Ashiya Clinic<\/a><\/td><\/tr>
Medical institution in charge of transplantation :<\/td>Luke’s Ashiya Clinic<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n

<\/span>Information at the time of initial medical examination<\/span><\/h3>\n\n
Disease name :<\/td>ASD<\/td><\/tr>
Time of onset :<\/td>Diagnosis at age 6<\/td><\/tr>
Transplant Purpose: To<\/td>Improvement of disease<\/td><\/tr>
Chief complaint :<\/td>\u30fb\u81ea\u9589\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u75c7\u306b\u3088\u308b\u75c7\u72b6\u30fbADHD(\u6ce8\u610f\u6b20\u5982\u30fb\u591a\u52d5\u75c7)\u30fb\u8efd\u5ea6\u77e5\u7684\u969c\u5bb3<\/td><\/tr>
History:<\/td>Nothing<\/td><\/tr>
Background, family history, lifestyle, supplement use, etc :<\/td>Nothing<\/td><\/tr><\/tbody><\/table><\/figure>\n\n

<\/span>Transplant Information<\/span><\/h3>\n\n
Transplantation period: from<\/td>2023\/8\/30\u301c2023\/10\/4<\/td><\/tr>
Number of transplants :<\/td>6 transplants<\/td><\/tr><\/tbody><\/table><\/figure>\n\n
Change from first transplant to end of transplant :<\/td><\/tr>
\u30101\u56de\u76ee\u79fb\u690d\u6642\u3011\u30fb\u7740\u66ff\u3048\u3092\u5acc\u304c\u3063\u305f\u3002\u300e\u691c\u67fb\u30d1\u30f3\u30c4\u304c\u6c17\u6301\u3061\u60aa\u3044\u3002\u7537\u6027\u306e\u524d\u3067\u30d1\u30f3\u30c4\u305a\u308c\u305f\u3089\u6065\u305a\u304b\u3057\u3044\u300f\u3068\u306e\u3053\u3068\u3002\u30fb\u79fb\u690d\u306e\u3053\u3068\u306f\u300e\u304a\u5c3b\u304b\u3089\u30c1\u30af\u30c3\u3068\u5165\u308c\u308b\u300f\u3068\u805e\u3044\u3066\u304d\u305f\u3002\u79fb\u690d\u306b\u3064\u3044\u3066\u306f\u53d7\u3051\u5165\u308c\u3066\u3044\u308b\u3002\u30fb\u8179\u9cf4\u5f31\u3044\u3002\u672c\u65e5\u6392\u4fbf\u306a\u3057\u3002\u8868\u60c5\u306f\u660e\u308b\u304f\u3001\u6bcd\u89aa\u3068\u306f\u8ac7\u7b11\u3057\u3066\u3044\u305f\u3002\u30fb\u79fb\u690d\u6642\u3001\u58f0\u304b\u3051\u3059\u308b\u3082\u4f53\u306b\u529b\u304c\u5165\u3063\u3066\u3057\u307e\u3063\u305f\u3002\u30fb\u51e6\u7f6e\u306f\u30b9\u30e0\u30fc\u30ba\u306b\u7d42\u4e86\u3059\u308b\u3002\u79fb\u690d\u5f8c10\u5206\u304f\u3089\u3044\u3067\u30c8\u30a4\u30ec\u5e0c\u671b\u3042\u308b\u304c\u300120\u5206\u5f8c\u3001\u6392\u5c3f\u306e\u307f\u3060\u3063\u305f\u3002\u30102\u56de\u76ee\u79fb\u690d\u6642\u3011\u30fb\u5909\u5316\u306a\u3057\u3002\u7720\u308a\u304c\u6d45\u304f\u3001\u671d\u8d77\u304d\u308b\u306e\u306b\u6642\u9593\u3092\u8981\u3059\u308b\u3002\u30fb\u666e\u6bb5\u306f\u3001\u6a5f\u5acc\u826f\u304f\u904e\u3054\u3057\u3066\u304a\u308a\u3001\u5927\u304d\u306a\u58f0\u3092\u51fa\u3057\u3066\u3044\u308b\u3002\u30fb\u79fb\u690d\u5f53\u65e5\u306e\u4fbf\u306f\u30b3\u30ed\u30b3\u30ed\u3060\u3063\u305f\u304c\u3001\u524d\u56de\u306e\u79fb\u690d\u5f8c\u304b\u3089\u529b\u307e\u305a\u306b\u6392\u4fbf\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3002\u30fb\u9759\u304b\u306b\u904e\u3054\u3057\u3066\u3044\u305f\u3002\u79fb\u690d\u3082\u30b9\u30e0\u30fc\u30ba\u306b\u7d42\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u3002\u30103\u56de\u76ee\u79fb\u690d\u6642\u3011\u30fb\u5909\u5316\u306a\u3057\u3002\u30fb\u6c17\u5206\u9ad8\u63da\u304c\u898b\u3089\u308c\u305f\uff08\u4f11\u85ac\u4e2d\u306e\u305f\u3081\uff1f\uff09\u3002\u30fb\u591c\u9593\u5bdd\u3064\u304d\u304c\u60aa\u304f\u3001\u7720\u308a\u304c\u6d45\u3044\u3002\u30fb\u300e\u4ed6\u306e\u4eba\u3082\u3053\u308c\uff08\u79fb\u690d\uff09\u3057\u3066\u3044\u308b\u306e\uff1f\u300f\u3001\u300e\u306a\u3093\u3067\u79c1\u306f\u3057\u3066\u308b\u306e\uff1f\u300f\u306a\u3069\u8cea\u554f\u304c\u591a\u3044\u3002\u30fb\u8868\u60c5\u306f\u7a4f\u3084\u304b\u3002\u5f85\u3061\u6642\u9593\u306b\u3042\u3063\u3061\u3080\u3044\u3066\u307b\u3044\u3092\u3057\u3066\u904a\u3093\u3067\u3044\u305f\u3002\u30fb\u751f\u74063\u65e5\u76ee\u3002\u75db\u307f\u306e\u8a34\u3048\u306a\u3057\u3002\u30fb\u76f4\u8178\u8a3a\u6642\u529b\u307f\u3042\u308b\u304c\u30b9\u30e0\u30fc\u30ba\u306b\u7d42\u4e86\u3057\u305f\u3002\u30104\u56de\u76ee\u79fb\u690d\u6642\u3011\u30fb\u524d\u56de\u79fb\u690d\u5f8c\u3001\u4e0b\u75e2\u304c3\u65e5\u9593\u7d9a\u3044\u305f\u3002\u4ee5\u5f8c3\u65e5\u9593\u306f\u6392\u4fbf\u304c\u306a\u3044\u3002\u30fb\u904b\u52d5\u4f1a\u306e\u75b2\u308c\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3001\u591c\u306e\u5bdd\u3064\u304d\u304c\u826f\u304f\u306a\u3063\u305f\u3002\u30fb\u6a5f\u5acc\u306f\u826f\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306e\u30dd\u30b9\u30bf\u30fc\u898b\u306a\u304c\u3089\u3001\u8cea\u554f\u3057\u3066\u3044\u305f\u3002\u30fb\u8179\u9cf4\u5f31\u3044\u305f\u3081\u4f53\u4f4d\u4ea4\u63db\u30923\u5468\u884c\u306a\u3063\u305f\u304c\u3001\u3084\u306f\u308a\u5f31\u3081\u3002\u30fb\u76f4\u8178\u8a3a\u5bdf\u6642\u3001\u4fbf\u304c\u809b\u9580\u8fd1\u304f\u307e\u3067\u304d\u3066\u3044\u3066\u3082\u4fbf\u610f\u304c\u306a\u3044\u69d8\u5b50\u3002\u79fb\u690d\u306f\u30b9\u30e0\u30fc\u30ba\u306b\u3067\u304d\u305f\u3002\u30105\u56de\u76ee\u79fb\u690d\u6642\u3011\u30fb\u524d\u56de\u79fb\u690d\u65e5\u3068\u7fcc\u65e5\u306b\u6392\u4fbf\u3042\u308a\u3002\u305d\u306e\u5f8c3\u65e5\u9593\u306a\u304f\u3001\u79fb\u690d\u65e5\u524d\u65e5\u3068\u5f53\u65e5\u306b\u6392\u4fbf\u3042\u308a\u3002\u30fb\u8179\u9cf4\u5f31\u3081\u3002\u8868\u60c5\u306f\u7a4f\u3084\u304b\u3002\u3088\u304f\u4f1a\u8a71\u3057\u3066\u3044\u305f\u3002\u79fb\u690d\u30b9\u30e0\u30fc\u30ba\u306b\u7d42\u4e86\u3057\u305f\u3002\u30106\u56de\u76ee\u79fb\u690d\u6642\u3011\u30fb\u5909\u5316\u306f\u611f\u3058\u3066\u3044\u306a\u3044\u3002\u30fb\u4ee5\u524d\u3088\u308a\u7761\u7720\u304c\u53d6\u308c\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3002\u4eca\u90311\u56de\u3060\u3051\u671d\u306e\u76ee\u899a\u3081\u304c\u60aa\u3044\u65e5\u304c\u3042\u3063\u305f\u3002\u30fb\u5b66\u6821\u304b\u3089\u306f\u30c6\u30f3\u30b7\u30e7\u30f3\u304c\u9ad8\u3044\u65e5\u304c\u591a\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u3002\u30fb\u30db\u30e9\u30fc\u304c\u597d\u304d\u3067\u3001\u6ce3\u3044\u3066\u3044\u308b\u6642\u306b\u30d1\u30af\u30d1\u30af\u3068\u53e3\u304c\u52d5\u304f\u4e38\u3044\u3082\u306e\u304c\u898b\u3048\u305f\u308a\u3001\u6df1\u591c\u306b\u58f0\u304c\u805e\u3053\u3048\u305f\u308a\u3059\u308b\u8a71\u3092\u305f\u304f\u3055\u3093\u3057\u3066\u3044\u305f\u3002\u30fb\u79fb\u690d\u306f\u30b9\u30e0\u30fc\u30ba\u306b\u7d42\u4e86\u3057\u305f\u3002<\/td><\/tr><\/tbody><\/table><\/figure>\n\n
Changes after completion of transplant :<\/td><\/tr>
\u30108\u9031\u76ee\u6642\u70b9\u3011\u30fb\u79fb\u690d\u3067\u5927\u304d\u304f\u5909\u308f\u3063\u305f\u611f\u3058\u306f\u306a\u3044\u3002\u30fb\u3053\u3060\u308f\u308a\u304c\u5f37\u3044\u3002\u81ea\u5206\u306e\u3053\u3060\u308f\u308a\u306e\u65b9\u6cd5\u3067\u8a08\u7b97\u3092\u3057\u3088\u3046\u3068\u3059\u308b\u3002\u30fb\u5207\u308a\u66ff\u3048\u306f\u5c11\u3057\u65e9\u304f\u306a\u3063\u305f\u5370\u8c61\u3002\u843d\u3061\u7740\u304d\u304c\u306a\u3044\u306e\u306f\u5909\u308f\u3089\u306a\u3044\u3002\u30fb\u671d\u306f\u81ea\u5206\u3067\u8d77\u304d\u3066\u304f\u308b\u3053\u3068\u304c\u5897\u3048\u305f\u3002\u671d\u3001\u3050\u305a\u308b\u3053\u3068\u304c\u306a\u304f\u306a\u3063\u305f\u3002\u30fb\u9045\u523b\u304c\u6e1b\u3063\u305f\u3002\u5b66\u6821\u304b\u3089\u306f\u300e\u590f\u4f11\u307f\u524d\u306f\u5348\u524d\u4e2d\u304b\u3089\u7720\u6c17\u304c\u3042\u3063\u305f\u304c\u3001\u305d\u308c\u304c\u306a\u304f\u306a\u3063\u305f\u3002\u4ee3\u308f\u308a\u306b\u3001\u304a\u3057\u3083\u3079\u308a\u304c\u3046\u308b\u3055\u304f\u306a\u3063\u305f\u3002\u6388\u696d\u4e2d\u306f\u6b4c\u3092\u6b4c\u3046\u3088\u3046\u306b\u306a\u3063\u305f\u300f\u3068\u5831\u544a\u304c\u3042\u3063\u305f\u3002\u30fbTPO\u304c\u8aad\u3081\u306a\u3044\u306e\u306f\u5909\u308f\u3089\u306a\u3044\u3002\u30fb\u4e57\u308a\u7269\u306b\u9759\u304b\u306b\u4e57\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u305f\uff08\u5909\u5316\uff09\u3002\u301018\u9031\u76ee\u6642\u70b9\u3011\u30fb\u96c6\u4e2d\u529b\u304c\u51fa\u3066\u304d\u305f\u3002\u5b66\u6821\u306e\u6388\u696d\u3067\u65b0\u805e\u3092\u4f5c\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u3002\u6821\u5916\u5b66\u7fd2\u3082\u3067\u304d\u305f\u3002\u30fb\u5b66\u6821\u3067\u306f\u6642\u9593\u3092\u6c17\u306b\u3059\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u9045\u523b\u304c\u306a\u304f\u306a\u3063\u305f\u3002\u30fb\u304a\u3057\u3083\u3079\u308a\u306f\u6b62\u307e\u3089\u306a\u3044(\u591a\u52d5\u306e\u85ac\u3092\u3084\u3081\u3066\u3044\u308b\u5f71\u97ff\uff1f)\u3002\u6388\u696d\u4e2d\u306e\u6b4c\u306f\u6b4c\u308f\u306a\u304f\u306a\u3063\u305f\u3002\u30fb\u4e57\u308a\u7269\u306b\u9759\u304b\u306b\u4e57\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3002\u30fb\u79fb\u690d\u3067\u826f\u304f\u306a\u3063\u305f\u90e8\u5206\u3082\u3042\u308b\u304c\u3001ADHD\u306e\u75c7\u72b6\u304c\u51fa\u3066\u3044\u308b\u3002\u30fb\u5bdd\u3064\u304d\u306f\u60aa\u3044\u3002\u301030\u9031\u76ee\u6642\u70b9\u3011\u30fb\u79fb\u690d\u5f8c\u3001\u4fbf\u901a\u306e\u8abf\u5b50\u826f\u304f\u306a\u308a\u3001\u7dad\u6301\u3067\u304d\u3066\u3044\u308b\u3002\u30fb\u8179\u90e8\u81a8\u6e80\u611f\u306a\u3057\u3002\u56f0\u3063\u3066\u3044\u308b\u3053\u3068\u3082\u306a\u3044\u3002\u30fb\u7647\u766a\u306f\u306a\u304f\u306a\u3063\u305f\u3002\u30ad\u30fc\u30ad\u30fc\u306a\u3089\u306a\u304f\u306a\u3063\u305f\u3002\u30fb\u96c6\u4e2d\u529b\u3042\u308b\u6642\u3068\u306a\u3044\u6642\u306e\u5dee\u304c\u6fc0\u3057\u3044\u3002\u9045\u523b\u306f\u306a\u3044\u3002\u30fb\u591a\u52d5\u306e\u5074\u9762\u3001\u885d\u52d5\u6027\u306f\u307e\u3060\u3042\u308b\u3002\u3072\u3069\u304f\u306f\u306a\u3044\u3002\u85ac\u4e2d\u6b62\u3057\u3066\u3044\u308b\u306e\u3067\u82e5\u5e72\u76ee\u7acb\u3064\u90e8\u5206\u306f\u3042\u308b\u3002\u30fb\u7b11\u9854\u3042\u308a\u3002\u89e6\u308b\u3068\u3001\u89e6\u3063\u305f\u6240\u3092\u6255\u3044\u3055\u3089\u3046\u52d5\u4f5c\u3042\u308a\u3002<\/td><\/tr><\/tbody><\/table><\/figure>\n\n

<\/span>Intestinal flora balance Comparative data<\/span><\/h3>\n\n
\"\"<\/figure>\n\n

<\/span>Evaluation and Discussion<\/span><\/h3>\n\n
Transplant General Comments and Discussion :<\/td><\/tr>
In addition to improvement in abnormal bowel movements, there was improvement in tantrums.As for hyperactivity and impulsivity, there was not much change.It is presumed that the degree of effectiveness may vary depending on the symptoms.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n

… and upwards<\/p>\n","protected":false},"excerpt":{"rendered":"Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. Basic Information Patients :12-year-old girlAttending physician :Luke’s Ashiya ClinicMedical institution in charge of transplantation :Luke’s Ashiya […]","protected":false},"author":1,"featured_media":13989,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[109],"tags":[141,88],"class_list":["post-14146","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fmt_cases","tag-asd","tag-lukes-ashiya-clinic"],"acf":[],"yoast_head":"\n12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fmt-japan.org\/en\/post\/14146\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report - \u8178\u5185\u30d5\u30ed\u30fc\u30e9\u79fb\u690d\u81e8\u5e8a\u7814\u7a76\u4f1a\" \/>\n<meta property=\"og:description\" content=\"Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. 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