Intestinal flora transplantation and case studies

Fecal microflora transplant case report] Other diseases (chronic sinusitis, etc.) 80s female

Case presentation Female in her 80s, other diseases

summary

Case presentation Female in her 80s, other diseases

Basic Information

Patients : 80’s Female
Attending physician : Life Clinic Tateshina
Medical institution in charge of transplantation : Life Clinic Tateshina

Information at the time of initial medical examination

Disease name : Chronic sinusitis, primary biliary cholangitis cirrhosis, dementia
Time of onset : More than 20 years ago
Transplant Purpose: To
Fatigable, improved constitution
Chief complaint : Fatigue, redness around eyes, itching discomfort, short-term memory loss Emotional incontinence
Medications and supplements : MEDICATION: URSO (100) 3T3 X N SUPPLEMENT: TA65
Medical history : none in particular
Background, family history, lifestyle, supplement use, etc :

Transplant Information

Transplantation period: from August 26, 2019 – November 5, 2019
Number of transplants : 6 times
Change from first transplant to end of transplant :
Conducted 6 transplants【1st transplantation questionnaire】 Family member (transplant recipient) requested a flora transplant in the hope that it would be effective for primary biliary cholangitis and depression. 【2nd transplantation questionnaire】 The redness around the eyes on the face was removed on the first day after the last transplant. He stopped scratching his nose. Fungal-like dermatitis on the anterior chest after 1 week also showed improvement. 【3rd transplantation questionnaire】 He has dementia and usually forgets that his son is coming home on Tuesdays, but last week he said himself that his son was coming home to Tokyo. This is the first time since he was diagnosed with dementia and entered a nursing home. The redness and itching around his eyes continues to improve. I also feel that he is becoming more honest with himself. 【4th transplantation questionnaire】 Crying face and emotional incontinence seem to have decreased. 【5th transplantation questionnaire】 There was no subjective impression that anything had improved, but her son said that the redness of her eyelids had been removed, that her eyes were brighter, and that her speech had increased, giving the impression that her cognitive functions had improved. He always cries due to emotional incontinence when his son leaves, but at the end of the third session, there was no emotional incontinence and he uttered such words as he will miss him, and after the fourth session, he expressed his loneliness. He acted as if others could understand him. When changing the date of the next transplant, his son wrote down the date, but after the fourth transplant, he no longer felt anxious or did not have to write down the date. 【6th transplantation questionnaire】 The eye area is in very good condition and there is no redness. There is a trend of improvement in dementia symptoms, and the quality of sleep is improving.
Changes after completion of transplant :
Generally, the family’s impression is that the sinusitis symptoms, including redness around the eyes, have improved. The impression is that emotional incontinence is gone and short-term memory is improving.

Evaluation and Discussion

Transplant Evaluation : Clear improvement of symptoms
< Intestinal flora balance 1st data > < Intestinal flora balance 2nd data >
His/her experience (from the questionnaire) :
After the first one transplant, the red area around my eyes disappeared. I started to feel more energetic and cheerful. I can see how the intestines have such an impact on our human condition and mental vitality.
Adverse events: No
Nothing
Transplant General Comments and Discussion :
The son, not the patient, was positive about the transplantation, and the transplantation was able to proceed with a positive impression from the beginning. The patient’s chronic sinusitis symptoms and peripheral dementia symptoms described above have improved, and improvement of primary biliary cholangitis is expected in the future. He commented that he is considering another transplant in the future.
… and upwards
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