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Intestinal flora transplantation and case studies

Ulcerative colitis (IBS) and small intestinal bacterial growth (SIBO) in a man in his 50s -Case report of fecal microbiota transplantation

Case presentation Male in his 50s with ulcerative colitis (IBS) and small intestinal bacterial growth (SIBO)

summary

After three transplants, the patient’s symptoms improved slightly, but he is still not satisfied with the results.

Basic Information

Patients : Male in his 50s
Attending physician : Luke’s Ashiya Clinic
Medical institution in charge of transplantation : Luke’s Ashiya Clinic

Information at the time of initial medical examination

Disease name : Small intestinal bacterial overgrowth (SIBO)
At onset : Around March 2018
Transplant Purpose: To Improvement of disease
Chief complaint : He has been diagnosed with small intestinal dysbiosis. He always feels his intestines are tense and he tends to be constipated. Since the onset of this condition, she feels tired and weak.
Medical history : In March 2018, she developed an inguinal hernia, which improved with surgery. Intestinal problems began shortly thereafter.
Background, family history, lifestyle, supplement use, etc : Chinese herbal medicine, supplements, etc.

Transplant Information

Transplantation period: from 2021/12/2~2022/1/7
Number of transplants : 3 transplants

Change from first transplant to end of transplant :

No obvious improvement in symptoms immediately after the end of the third session. Two weeks later, the symptoms of gas have slightly lessened.

【1st transplantation questionnaire】
（From a patient)
Concerned about residual stools. Difficulty in getting rid of fatigue. I am not good at or afraid of blood sampling. Drinking hydrogen NanoGAS water makes my stools loose, so I don’t drink it every day.

Evaluation after the first transplantation]FMT against IBS SIBO. gas volume is slightly lighter.

【2nd transplantation questionnaire】
Intestinal peristalsis, better than last time. Soft abdomen.
(From a patient)
I consume large amounts of seaweed and lotus root. I began to feel tension in my lower abdomen. As for water intake, she tries to drink a lot of water at night, although it is difficult to take it during the day due to her work. There is no change in the condition of his stools.

【3rd transplantation questionnaire】
(From a patient)
Bristol Scale Type 4 up to 3 days before, 1-2 times/day.
Constipation since yesterday, Type 1, once/day. No abdominal tension, low fluid intake, strong cold sensation in lower extremities.

[Third post-implantation evaluation].
There was some improvement in symptoms from before FMT, but bloating and discomfort remained.

 

Intestinal flora balance Comparative data

 

Evaluation and Discussion

Transplant Evaluation : Mild improvement of symptoms (improvement of constipation)
Adverse events: No Nothing

 

Transplant Evaluation :
FMT for irritable bowel syndrome (IBS) gas type and small intestinal bacterial overgrowth (SIBO). Slightly less gas; some improvement from pre-FMT, but still bloating and discomfort.

 

… and upwards

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Ulcerative colitis (IBS) and small intestinal bacterial growth (SIBO) in a man in his 50s -Case report of fecal microbiota transplantation

Case presentation Male in his 50s with ulcerative colitis (IBS) and small intestinal bacterial growth (SIBO) summary After three transplants, the patient’s symptoms improved slightly, but he is still not satisfied with the results. Basic Information Patients : Male in his 50s Attending physician : Luke’s Ashiya Clinic Medical institution in charge of transplantation : […]