Autism Spectrum Disorder and Other Disorders in a Female in her 40s – Fecal Microbiota Transplantation Case Report
Case presentation Female in her 40s, autistic spectrum disorder, other disorders
summary
After the first transplant, her anxiety and other feelings disappeared.
Basic Information
| Patients : | Woman in her 40s |
| Attending physician : | Natural Art Clinic |
| Medical institution in charge of transplantation : | Natural Art Clinic |
Information at the time of initial medical examination
| Disease name : | Autism Spectrum Disorders, Other Disorders |
| At onset : | Since as far back as I can remember. Diagnosed in 2016. |
| Transplant Purpose: To | Improvement of symptoms such as irritability, tantrums, tiredness, diarrhea, gas, etc. Skin problems (including atopic dermatitis), constitutional improvement |
| Chief complaint : |
Although I was diagnosed only as an adult, I have always had elements of social anxiety disorder since childhood. I feel fear and anxiety about everything I don’t understand and get extremely nervous when I go out in public.
She had HSP (HSS) and often felt uncomfortable with various stimuli and information in his daily life, making it difficult for him to live. |
| Medications being taken : | |
| Medical history : | |
| Background, family history, lifestyle, supplement use, etc : |
Transplant Information
| Transplantation period: from | July 16, 2021 – August 17, 2021 |
| Number of transplants : | 6 times |
| Change from first transplant to end of transplant : |
|
【1st transplantation questionnaire】 【2nd transplantation questionnaire】 【3rd transplantation questionnaire】 【4th transplantation questionnaire】 【5th transplantation questionnaire】 【6th transplantation questionnaire】 【Questionnaire at the 2 month post-inspection】 |
Intestinal flora balance Comparative data

| Blood test changes : | Not implemented |
| CHANGE IN POMS2 SCORE : | Not implemented |
| His/her experience (from the questionnaire) : |
Evaluation and Discussion
| Transplant Evaluation : | Clear improvement of symptoms |
| Adverse events: No | Nothing |
| Changes after completion of transplant : |
| Anxiety disappeared after the first transplant. Stools also improved. Felt the best after the first transplant, but maintained good condition after that. No longer anxious or irritable. Her diet has also changed significantly from before the transplant. |
| Transplant General Comments and Discussion : |
| As mentioned above, the effects were felt from after the first transplant. Anxiety decreased, and subsequently, impatience and irritability also disappeared. Normalization of stools also normalized. |
… and upwards
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Fecal microbiota transplantation results *As of September , 2025
The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others

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