Ulcerative colitis, male in his 60s -Fecal microflora transplant case report
Case presentation: Male in his 60s, ulcerative colitis (under observation)
summary
He has had bloody stools and abdominal pain since January 2018. Symptoms persisted and was diagnosed with ulcerative colitis in November 2018 after colonoscopy and other tests. She started Lialda 4800 mg, but her symptoms persisted and her weight decreased by 4 kg, so she requested intestinal flora transplantation. Six transplants were performed: 1) on August 26, 2) on August 28, 3) on September 2, 4) on September 9, 5) on September 18, and 6) on September 25, 2019. Gradually, abdominal pain and diarrhea disappeared, as did bloody stools. No side effects associated with transplantation were observed.
Basic Information
| Patients : | 60s Male |
| Attending physician : | Resort Care House Tateshina Corporation (Life Clinic Tateshina) Medical Corporation Keimeikai Kimura Hospital |
| Medical institution in charge of transplantation : | Resort Care House Tateshina Corporation (Life Clinic Tateshina) Medical Corporation Keimeikai Kimura Hospital |
Information at the time of initial medical examination
| Disease name : | ulcerative colitis |
| At onset : | At onset January 2018 |
| Transplant Purpose: To | Diarrhea, abdominal pain, bloody stools |
| Chief complaint : | Diarrhea/abdominal pain |
| Medications being taken : | Lialda 4800 mg/day |
| Medical history : | high blood pressure |
| Background, family history, lifestyle, supplement use, etc : | He had been diagnosed with ulcerative colitis at another hospital, but his symptoms persisted and he came to our hospital after learning about the Intestinal Flora Transplant Clinical Research Group from our website. |
Transplant Information
| Transplantation period: from | August 26, 2019 – September 25, 2019 |
| Number of transplants : | 6 times |
| Change from first transplant to end of transplant : |
| Gradually, abdominal pain and diarrhea disappeared, as did bloody stools. 【1st transplantation questionnaire】 Lower abdominal pain and soft stools when eating. 【2nd transplantation questionnaire】 No change since last time. 【3rd transplantation questionnaire】 No change No abdominal pain or diarrhea, although he has also started eating meat. 【4th transplantation questionnaire】 No abdominal pain, appetite has improved. 【5th transplantation questionnaire】 No abdominal pain, stools are a little soft Food is gradually becoming a normal diet, although no fried food is being eaten No diarrhea, no abdominal pain |
| Changes after completion of transplant : |
| After the end of the program, he has slightly soft stools, sometimes 2 times/day, but it is not painful. He is now able to eat the same food as his family. |
Evaluation and Discussion
| Transplant Evaluation : | Clear improvement of symptoms |
| Pre- and post-transplant flora balance test changes:. | Waiting for test results after transplant |
| Blood test changes:. | Waiting for test results after transplant |
| POMS2 SCORE CHANGE:. | Waiting for test results after transplant |
＜Intestinal flora balance before and after transplantation＞
| His/her experience (from the questionnaire) : |
| None at present |
| Adverse events: No |
| Nothing |
| Transplant General Comments and Discussion : |
| The patient continues to take 4800 mg of Lialda, but no longer has diarrhea, abdominal pain, or bloody stools, and the intestinal flora transplant has been extremely useful. |
… and upwards
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