Irritable bowel syndrome in a man in his 50’s – Case report of fecal microbiota transplantation
Case presentation: Male in his 50s, irritable bowel syndrome (under observation)
summary
IBS SYMPTOMS APPEARED ABOUT 20 YEARS AGO, DIARRHEA WAS THE MAIN SYMPTOM, ABOUT 20 TIMES A DAY AT MOST, AND THE SYMPTOMS WORSENED DUE TO WORK STRESS, ETC. IN 2012, HE RETIRED AND BECAME SELF-EMPLOYED, AND THE STRESS WAS REDUCED, BUT THE SYMPTOMS CONTINUED. 2014, HE HAD A DESCENDING COLON RESECTION DUE TO DIVERTICULITIS OF THE COLON, AT WHICH TIME HE TOOK ABS MEDICATION, AND HIS IBS SYMPTOMS WERE ALLEVIATED. IBS SYMPTOMS DECREASED AND DIARRHEA HAS DECREASED TO 4-5 TIMES A DAY. CURRENTLY TAKING IRIBO. VISITED OUR OUTPATIENT CLINIC ON OCTOBER 31, 2019 AND UNDERWENT 3 INTESTINAL FLORA TRANSPLANTATION SESSIONS FROM NOVEMBER 18, 2019. PATIENT IS UNDER OBSERVATION.
Basic Information
| Patients : | 50s Male |
| Attending physician : | Medical Corporation Sakurashinkai Sante Clinic |
| Medical institution in charge of transplantation : | Medical Corporation Sakurashinkai Sante Clinic |
Information at the time of initial medical examination
| Disease name : | irritable bowel syndrome |
| At onset : | About 20 years ago |
| Transplant Purpose: To | Diarrhea, frequent gas |
| Chief complaint : | diarrhea symptom |
| Medications being taken : | man who allegedly pursues a career at the expense of love, feminine interests, etc. |
| Medical history : | 2014 Descending colon resection due to diverticulitis of the colon |
| Background, family history, lifestyle, supplement use, etc : | Has been treated at a local doctor since 1994 No use of supplements Consumes a lot of vegetables |
Transplant Information
| Transplantation period: from | November 18, 2019 – November 22, 2019 |
| Number of transplants : | 3 times |
| Change from first transplant to end of transplant : |
| Decreased frequency of diarrhea, early postprandial bowel movements, decreased emissions 【1st transplantation questionnaire】 2 stools/day. There were signs of nervousness. 【2nd transplantation questionnaire】 Stool frequency: 2 times/day. No abdominal symptoms. 【3rd transplantation questionnaire】 Gas was steadily decreasing, she was no longer going to the toilet immediately after meals, and the frequency of stools itself was also decreasing. |
| Changes after completion of transplant : |
| Now following |
Evaluation and Discussion
| Transplant Evaluation : | Mild improvement of symptoms |
| Pre- and post-transplant flora balance test changes:. | under inspection |
| Blood test changes:. | under inspection |
| POMS2 SCORE CHANGE:. | under inspection |
＜Intestinal flora balance before transplant data＞
＜Intestinal flora balance Post-transplant data＞ Examination to be conducted
| His/her experience (from the questionnaire) : |
| Very satisfied with treatment Symptom improvement still mild |
| Adverse events: No |
| Nothing |
| Transplant General Comments and Discussion : |
| After the second transplant, the frequency of diarrhea has decreased and he no longer has the urge to have a bowel movement within 30 minutes after a meal. She is now under less stress and is trying to lead a regular life and get enough sleep, so we can expect further improvement in her symptoms. |
… and upwards
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Fecal microbiota transplantation results *As of September , 2025
The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others
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