Constipation Syndrome, Female in her 50s -Fecal microflora transplant case report
Case presentation: Female in her 50s (Chinese nationality), constipation (under observation)
summary
In August of this year, he visited our outpatient clinic for improvement of constipation symptoms. After conducting an intestinal flora balance test, 6 transplants were performed based on twice-daily transplants. During the transplantation, there was a slight improvement in constipation symptoms, but diarrhea symptoms were also observed at the same time. A flora balance examination is scheduled to be performed within a year after transplantation.
Basic Information
| Patients : | 50’s Female |
| Attending physician : | Medical Corporation Sakurashinkai Sante Clinic |
| Medical institution in charge of transplantation : | Medical Corporation Sakurashinkai Sante Clinic |
Information at the time of initial medical examination
| Disease name : | constipation |
| At onset : | About 20 years ago |
| Transplant Purpose: To | constipation |
| Chief complaint : | constipation |
| Medications being taken : | Nothing |
| Medical history : | 2000 Uterine cyst excision, said to be HBV carrier since age 26, but no liver dysfunction |
| Background, family history, lifestyle, supplement use, etc : | He has been suffering from constipation symptoms for about 20 years. visited our outpatient clinic in August 2019. After flora balance test, applied for intestinal flora transplant. Family history: father has esophageal cancer, currently using DHEA. |
Transplant Information
| Transplantation period: from | 2019年10月8日〜2019年10月11日 |
| Number of transplants : | 6 times |
| Change from first transplant to end of transplant : |
| Improvement of constipation symptoms during transplantation was observed. 【1st transplantation questionnaire】 Patient complained of constipation and had to have a bowel movement only once every 2 days. 【2nd transplantation questionnaire】 One watery stool was passed after transplant. No abdominal symptoms. 【3rd transplantation questionnaire】 No abdominal symptoms. 【4th transplantation questionnaire】 I felt like going to the toilet immediately after transplant. No abdominal symptoms. 【5th transplantation questionnaire】 No abdominal symptoms. 6th transplant interview No abdominal symptoms. No defecation. |
| Changes after completion of transplant : |
| Flora balance test will be performed after transplant. Currently under follow-up. |
Evaluation and Discussion
| Transplant Evaluation : | Mild improvement of symptoms |
| Pre- and post-transplant flora balance test changes:. | Post-transplant examination not performed |
| Blood test changes:. | Not implemented |
| POMS2 SCORE CHANGE:. | No inspection |
＜Intestinal flora balance before transplant data＞
| His/her experience (from the questionnaire) : |
| Mild improvement in symptoms – no change |
| Adverse events: No |
| Yes (mild) |
| Transplant General Comments and Discussion : |
| Constipation symptoms are improving, but diarrhea is also observed and bowel movements are not stable. The pre-transplant flora balance test showed a lack of flora diversity and dietary habits that need improvement, so it is important to improve the flora balance and normalize bowel movements. |
… and upwards
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The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others
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