Autism Spectrum Disorder 7-year-old boy -Fecal microbiota transplantation case report
Case presentation 7-year-old boy with autistic spectrum disorder
summary
A case of fecal microbiota transplantation for autism spectrum disorder (ASD). The patient was noticeably obsessive. After the first transplantation, he was able to get out of the car by himself, and he was able to change his mind. 30 weeks after the transplantation, his condition remained stable, which may be due to the transplantation.
Basic Information
| Patients : | 7 year old boy |
| Attending physician : | Luke’s Ashiya Clinic |
| Medical institution in charge of transplantation : | Luke’s Ashiya Clinic |
Information at the time of initial medical examination
| Disease name : | ASD |
| Time of onset : | Developmental delays noted at 1.5 year-old checkup. |
| Transplant Purpose: To | Improvement of disease |
| Chief complaint : | Insistence ∙ Inability to understand the situation around them Poor change of mind Weak outlook Difficulty in tackling things they are not good at Clumsiness of limbs |
| History: | The patient is followed up at the 1.5-year-old child’s checkup. He has been seeing a pediatric/child neurologist since the age of 2. Began occupational therapy, including gross motor and verbal prompting. Started small group therapy at age 3. ADHD/ASD tendencies. |
| Background, family history, lifestyle, supplement use, etc : | Nothing |
Transplant Information
| Transplantation period: from | 2023/7/6〜2023/8/10 |
| Number of transplants : | 6 transplants |
| Change from first transplant to end of transplant : |
| [During the first transplant] He was playing games and talking to his parents the whole time. He was moving his body during the rectal examination, saying “I don’t feel good,” but the transplant went smoothly. [During the second transplant]. She did not want to go to school, but she said, “I don’t like being away from my mom. I know I have to go to school. She resisted a little, but was able to hold her position during the transplant. [At the time of the third transplant It was difficult for him to make eye contact, but he gradually began to make eye contact. Since the second transplant, his behavior has calmed down. There was a decrease in standing and walking, and changes were seen in his response to voice calls, ease of following instructions, and talking about his feelings and wishes. [At the time of the fourth transplant] He is in a bad mood when the game is taken away from him. Every porting is smooth and easy. [At the time of the 5th transplant No stool without suppositories. [At the time of the 6th transplant The child became more aware of what he had to do, such as homework. Before the transplant, he was reluctant to do so, but once the transplant began, he calmed down. |
| Changes after completion of transplant : |
| I had an increase in hyperactivity and had trouble switching, but overall, my switching has improved. I became able to look at myself objectively and to be aware of things other than myself, and I felt as if my world had broadened. I became more aware of other people’s point of view. My understanding of stories improved. My obsession was eased. I am now able to catch up in natural conversation. Her vocabulary has increased, and she is now able to communicate her own situation and feelings, and to listen to what others have to say. They have become more active, such as riding their bicycles to their classmates’ houses. They are now able to imagine what the future holds for them. I have the impression that their growth has been accelerated by the transplantation. |
Intestinal flora balance Comparative data
Evaluation and Discussion
| Transplant General Comments and Discussion : |
| The change of mind was markedly better after the transplant, and miscommunication with the parents decreased. This is thought to be an effect of the transplantation. |
… and upwards
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Fecal microbiota transplantation results *As of September , 2025
The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others
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12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report
Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. Basic Information Patients :12-year-old girlAttending physician :Luke’s Ashiya ClinicMedical institution in charge of transplantation :Luke’s Ashiya […]
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6-year-old boy with autism spectrum disorder -Fecal microbiota transplant case report
Case presentation 6-year-old boy with autistic spectrum disorder summary A case of transplantation for autism spectrum disorder (ASD). The patient has difficulty in understanding his surroundings and tends to be hyperactive. The main complaint was lack of concentration. No significant change was observed after transplantation. Basic Information Patients :6 year old boyAttending physician :Luke’s Ashiya […]
