Autism Spectrum Disorder 8-year-old girl – Fecal microbiota transplantation case report
Case presentation 8-year-old girl with autism spectrum disorder
summary
A case of fecal microbiota transplantation for autism spectrum disorder (ASD) and scene silence. Although the patient’s silence in the examination room did not change after transplantation, he talked more with his family and had more days of good mood. This is thought to be an effect of the transplantation.
Basic Information
| Patients : | 8-year-old girl |
| Attending physician : | Luke’s Ashiya Clinic |
| Medical institution in charge of transplantation : | Luke’s Ashiya Clinic |
Information at the time of initial medical examination
| Disease name : | ASD |
| Time of onset : | November 2016 |
| Transplant Purpose: To | Improvement of disease |
| Chief complaint : | 3He was caught in a 3-year-old child’s medical checkup and was subsequently diagnosed on the autism spectrum at a pediatrician’s office. He was told that he did not speak at kindergarten from the age of 2.5 years old, and he had symptoms of being a scene-setter, and was diagnosed by a specialist in scene-setting disorder when he turned 3 years old. He was diagnosed at the age of 3 by a specialist in the field of autism. His height and weight were detected at his 4-month checkup, and he has been under observation ever since, starting treatment with growth hormone injections at the age of 5. At the age of 7, he was diagnosed with a developmental quotient (DQ) of 66 on a developmental examination. Currently, he is eccentric in that he has difficulty changing his mind, gets along with only one friend, wears only certain clothes, etc. |
| History: | Autism spectrum is rehabilitation and counseling. The scene is counseling. Hormone injections for short stature. |
| Background, family history, lifestyle, supplement use, etc : | He used to take iron, folic acid, and vitamin B6, but no longer does. |
Transplant Information
| Transplantation period: from | 2023/7/5〜2023/8/9 |
| Number of transplants : | 6 transplants |
| Change from first transplant to end of transplant : |
| At the time of the first transplant The patient looked nervous at the time of the first transplant, but had a smile on her face after the transplant was completed. [At the time of the second transplantation]. There was no discharge of bacterial fluid after the last transplant. The next day, there was a defecation, type4. After that, he had a bowel movement once every 2 days. No significant change. At the time of the third transplant] She is able to come to the clinic without any resistance. I feel that she is smiling more. Today, she was able to have a conversation instead of just speaking words. [At the time of the fourth transplant The mother said, “He talks a lot now. She is smiling. She smiled immediately after the catheter insertion, although her facial expression sometimes stiffened during the transplant. [At the time of the 5th transplant He comes to the hospital with his brother and mother with a smile on his face. They answer questions. [At the time of the sixth transplant]. Smiling. Speech is observed and conversation is possible. |
| Changes after completion of transplant : |
| There was a lot of burping for a period of time. After the sixth transplant, burping increased, but it was under control and gradually disappeared. The facial expressions became calmer and richer, and eye contact was more frequent. The scene is not so clear. He has a bowel movement once every two days. |
Intestinal flora balance Comparative data
Evaluation and Discussion
| Transplant General Comments and Discussion : |
| The scene did not improve, but conversations with family members increased. Mild burping appeared after the 6th transplant, but gradually disappeared. |
… and upwards
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Fecal microbiota transplantation results *As of September , 2025
The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others
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Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. Basic Information Patients :12-year-old girlAttending physician :Luke’s Ashiya ClinicMedical institution in charge of transplantation :Luke’s Ashiya […]
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6-year-old boy with autism spectrum disorder -Fecal microbiota transplant case report
Case presentation 6-year-old boy with autistic spectrum disorder summary A case of transplantation for autism spectrum disorder (ASD). The patient has difficulty in understanding his surroundings and tends to be hyperactive. The main complaint was lack of concentration. No significant change was observed after transplantation. Basic Information Patients :6 year old boyAttending physician :Luke’s Ashiya […]
