Intestinal flora transplantation and case studies

Autism Spectrum Disorder 11-year-old girl – Fecal microbiota transplantation case report

Case presentation 11-year-old girl with autism spectrum disorder

summary

He has tended to be hyperactive since his autism diagnosis. He rarely communicates and is unable to speak. He also has sleep disturbances. He is agitated and does not sleep well. He was initially resistant to the transplant but gradually became less resistant. His bowel movements improved, he started to sleep a little more, and he started to listen to what he was told.

Basic Information

Patients :11-year-old girl
Attending physician :Medical Corporation Haruna Clinic
Medical institution in charge of transplantation :Medical Corporation Haruna Clinic

Information at the time of initial medical examination

Disease name :ASD
Time of onset :10 months old
Transplant Purpose: ToImprovement of disease
Chief complaint :・こだわり
・言葉の不理解
・発語の遅れ
・多動傾向あり
・集中力がない
History:Nothing
Background, family history, lifestyle, supplement use, etc :Chinese herbal medicine, etc.

Transplant Information

Transplantation period: from2023/6/23〜2023/7/29
Number of transplants :6 transplants
Changes from the first transplant to the end of the transplant:
【1回目移植時】
多動症は変わらず。体温は測定できたが、血圧などは測定不可。

【2回目移植時】
・以前より少し指示が通りやすくなった。
・携帯電話を素直に貸してくれた。
・トイレに自分から行くようになった。
・2,3日に1回の便でべちゃっとしている。

【3回目移植時】
・素直に絵本などを返せるようになった。
・トイレにも自ら行くようになった。
・移植の際に少し抵抗があったようだが、激しい抵抗はなくなった。
・便通は4日に1回程度で、毎日出ることはないが便の質は良くなってきたように思われる。

【4回目移植時】
・機嫌よくしている。
・皮膚の方は変わらずかゆみがある様子。

【5回目移植時】
移植当日に熱が出たが、すぐに下がったため移植実施。

【6回目移植時】
・物分かりが良くなってきた感じがする。
・移植に対する抵抗も少なくなってきている。
Changes after completion of transplant :
I have been having better bowel movements, and they are coming out every day.
I am mentally calm.
He used to wander around during medical examinations, but is now able to sit in the chair.
The students are now able to make eye contact with each other when they are talking and seem to understand what is being said.
I enjoyed going to school and went on the school trip without any trouble.
Temperature measurement is possible, but blood pressure measurement is not.

Intestinal flora balance Comparative data

Evaluation and Discussion

Transplant General Comments and Discussion :
His bowel movements have improved with the transplant. Although he does not communicate, he sometimes listens to his voice, and his hyperactivity seems to be a little better. He is able to follow instructions more easily than before, and he feels that he understands things better. He is also getting some sleep. However, it is difficult to recognize a dramatic improvement, and the hyperactivity tendency has not changed.

… and upwards

Articles about other Intestinal flora transplantation and case studies

November 03, 2025 Atopy/AllergyAutism Spectrum DisorderconstipationFecal Microflora Transplantationirritable bowel syndromeOther Diseasestrack recordulcerative colitis

Fecal microbiota transplantation results *As of September , 2025

The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others

November 02, 2024 Autism Spectrum DisorderLuke's Ashiya Clinic

12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report

Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. Basic Information Patients :12-year-old girlAttending physician :Luke’s Ashiya ClinicMedical institution in charge of transplantation :Luke’s Ashiya […]

November 02, 2024 Autism Spectrum DisorderLuke's Ashiya Clinic

6-year-old boy with autism spectrum disorder -Fecal microbiota transplant case report

Case presentation 6-year-old boy with autistic spectrum disorder summary A case of transplantation for autism spectrum disorder (ASD). The patient has difficulty in understanding his surroundings and tends to be hyperactive. The main complaint was lack of concentration. No significant change was observed after transplantation. Basic Information Patients :6 year old boyAttending physician :Luke’s Ashiya […]