Intestinal flora transplantation and case studies

Autism Spectrum Disorder – 12-year-old boy – Fecal Microbiota Transplantation Case Report

Case presentation 12-year-old boy with autistic spectrum disorder

summary

The transplant was implemented in the hope that the same things would be said over and over again, that the patient would be less upset when warned, and that the unnecessary obsession would be eliminated. The family’s impression was that there was no significant change before and after the transplantation, but there was a significant change in the balance of the intestinal flora.

Basic Information

Patients :12-year-old boy
Attending physician :医療法人悠亜会 かわい内科クリニック
Medical institution in charge of transplantation :医療法人悠亜会 かわい内科クリニック

Information at the time of initial medical examination

Disease name :ASD
Time of onset :12 years old
Transplant Purpose: ToImprovement of disease
Chief complaint :Poor verbal communication
History:Nothing
Background, family history, lifestyle, supplement use, etc :Nothing

Transplant Information

Transplantation period: from2023/7/1〜2023/8/5
Number of transplants :6 transplants
Change from first transplant to end of transplant :
【1回目移植時】
最近の便はコロコロ。移植処置は問題なく終了。

【2回目移植時】
1回目移植後の変化は感じていない様子。本日排便なし。
移植処置に対する抵抗はなし。

【3回目移植時】
変化なし。

【4回目移植時】
変化なし。

【5回目移植時】
変化なし。

【6回目移植時】
変化なし。
Changes after completion of transplant :
・ご家族から見て大きな変化はないという様子。
・便は2日に1回。やや軟便だったのが、30週は同じペースで普通便になった。
・挨拶はできる。落ち着き無く診察室内をうろつくのは移植前と同様。
・腸音はやや微弱。
・ゲーズファインダーは問題無く施行できた。”指さし”の画面では『ペンギン』と答え「お名前は?」の質問に自分の氏名を答えることができていた。
・以前より、指示に素直に従う印象あり。

Intestinal flora balance Comparative data

Evaluation and Discussion

Transplant General Comments and Discussion :
I had expected to see the disappearance of the same things he says repeatedly, the backhandedness when I warn him, and his obsession with useless things (collecting eraser shavings, wiping water droplets from the kitchen sink and bathroom hand-washing bowl with a tissue, collecting hair on the living room floor with his palms, etc.), but my family’s impression was that there was no change before and after the transplantation. However, the family did not feel any change before and after the transplantation.
However, it is possible that these are more personality factors than autism.
In addition, significant changes in the intestinal flora balance have been observed, and we believe that changes may occur in the long term.

… and upwards

Articles about other Intestinal flora transplantation and case studies

November 03, 2025 Atopy/AllergyAutism Spectrum DisorderconstipationFecal Microflora Transplantationirritable bowel syndromeOther Diseasestrack recordulcerative colitis

Fecal microbiota transplantation results *As of September , 2025

The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others

November 02, 2024 Autism Spectrum DisorderLuke's Ashiya Clinic

12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report

Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. Basic Information Patients :12-year-old girlAttending physician :Luke’s Ashiya ClinicMedical institution in charge of transplantation :Luke’s Ashiya […]

November 02, 2024 Autism Spectrum DisorderLuke's Ashiya Clinic

6-year-old boy with autism spectrum disorder -Fecal microbiota transplant case report

Case presentation 6-year-old boy with autistic spectrum disorder summary A case of transplantation for autism spectrum disorder (ASD). The patient has difficulty in understanding his surroundings and tends to be hyperactive. The main complaint was lack of concentration. No significant change was observed after transplantation. Basic Information Patients :6 year old boyAttending physician :Luke’s Ashiya […]