Dysautonomia, male in his 20s -Case report of fecal microflora transplantation

Case presentation: Male in his 20s, autonomic ataxia

summary

Apathetic and hard to get motivated. She has been feeling a little more motivated and in a better mood since the second transplant. He used to feel sluggish upon waking up, but this has improved.

Basic Information

Information at the time of initial medical examination

Disease name :	Dysautonomia, atopy/allergy
At onset :	When I was a college student
Transplant Purpose: To	Improvement of disease, diarrhea, allergies (food, pollen, chemicals, etc.), etc.
Chief complaint :	He is lethargic, has mood swings, and has difficulty motivating himself. I am also very nervous. I also want to lose weight.
Medical history :	Nothing
Background, family history, lifestyle, supplement use, etc :	Butyric acid bacteria, antiallergic agents, etc.

Transplant Information

Transplantation period: from	2021/7/20~2023/9/28
Number of transplants :	6 transplants + 3 additional transplants

Change from first transplant to end of transplant :

I had been lethargic and unmotivated, but now I feel a little more motivated. The sluggishness upon waking up has also improved. Questionnaire at the time of the first transplant They tend to be nervous and anxious easily. He was quite nervous, so it took some time to insert it through his anus, but he relaxed after the implantation. Since he said that he often drinks refined sugar and other sugars, especially juice, I advised him to make sure he gets enough sugar from root vegetables and rice. 【2nd transplantation questionnaire】 After the first transplant, the fungal fluid appeared a short time later. He said he has never changed as a symptom, but neither has he worsened. He was lethargic and unmotivated and wanted to gain weight. 【3rd transplantation questionnaire】 After the second transplant, I started to feel a little more motivated. He also noted improvement in lethargy upon waking. 【4th transplantation questionnaire】 He is in better shape than before the transplant, but tends to have poor stools when nervous. 【5th transplantation questionnaire】 This time, he had a cold and took antibiotics, but they did not suit him, so he had fatigue and a bit of diarrhea. 【6th transplantation questionnaire】 Frequent diarrhea and a feeling of heaviness in the abdomen after eating. He tends to be nervous but calm. Colonoscopy showed no abnormality and he was diagnosed with irritable bowel syndrome. The bowel sounds were hypersensitive before the transplant, but returned to normal after the transplant. Questionnaire at the time of the first additional transplant I have been mentally anxious for a week now. He had been stable until then, but three days ago his stools became loose and today he had diarrhea three times. He was instructed to stop taking artificially sweetened beverages every day. Questionnaire at the time of the second additional transplant He is mentally calm and his bowel movements are in good shape. Questionnaire after 2nd additional transplant As for mood, it has mostly calmed down. Sometimes it was difficult to sleep at night due to heightened moods, but now I am able to sleep. Questionnaire at the time of the third additional transplant His tummy and mental health are calming down, but his stomach has been upset and he has diarrhea for the past 3 days.

Intestinal flora balance Comparative data

Evaluation and Discussion

Transplant Evaluation :	Mild improvement of symptoms
Adverse events: No	Nothing

Transplant Evaluation :

The first transplant did not show much change in symptoms. After the second transplant, I became less lethargic and unmotivated, and a little more motivated. His lethargy upon waking up has improved and he is motivated in the morning. He feels somewhat better after the transplant. After my sixth transplant, my mental health has not changed, but recently I have been experiencing diarrhea about 4-5 times, and I feel a little heavy in my lower abdomen after eating. Colonoscopy showed no abnormality and he was diagnosed with irritable bowel syndrome. Additional transplants are continuing as we monitor the situation.

… and upwards