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Intestinal flora transplantation and case studies

Ulcerative colitis (IBS) and small intestinal bacterial growth (SIBO) in a man in his 50s -Case report of fecal microbiota transplantation

Case presentation Male in his 50s with ulcerative colitis (IBS) and small intestinal bacterial growth (SIBO)

summary

After three transplants, the patient’s symptoms improved slightly, but he is still not satisfied with the results.

Basic Information

Patients : Male in his 50s
Attending physician : Luke’s Ashiya Clinic
Medical institution in charge of transplantation : Luke’s Ashiya Clinic

Information at the time of initial medical examination

Disease name : Small intestinal bacterial overgrowth (SIBO)
At onset : Around March 2018
Transplant Purpose: To Improvement of disease
Chief complaint : He has been diagnosed with small intestinal dysbiosis. He always feels his intestines are tense and he tends to be constipated. Since the onset of this condition, she feels tired and weak.
Medical history : In March 2018, she developed an inguinal hernia, which improved with surgery. Intestinal problems began shortly thereafter.
Background, family history, lifestyle, supplement use, etc : Chinese herbal medicine, supplements, etc.

Transplant Information

Transplantation period: from 2021/12/2~2022/1/7
Number of transplants : 3 transplants

Change from first transplant to end of transplant :

No obvious improvement in symptoms immediately after the end of the third session. Two weeks later, the symptoms of gas have slightly lessened.

【1st transplantation questionnaire】
（From a patient)
Concerned about residual stools. Difficulty in getting rid of fatigue. I am not good at or afraid of blood sampling. Drinking hydrogen NanoGAS water makes my stools loose, so I don’t drink it every day.

Evaluation after the first transplantation]FMT against IBS SIBO. gas volume is slightly lighter.

【2nd transplantation questionnaire】
Intestinal peristalsis, better than last time. Soft abdomen.
(From a patient)
I consume large amounts of seaweed and lotus root. I began to feel tension in my lower abdomen. As for water intake, she tries to drink a lot of water at night, although it is difficult to take it during the day due to her work. There is no change in the condition of his stools.

【3rd transplantation questionnaire】
(From a patient)
Bristol Scale Type 4 up to 3 days before, 1-2 times/day.
Constipation since yesterday, Type 1, once/day. No abdominal tension, low fluid intake, strong cold sensation in lower extremities.

[Third post-implantation evaluation].
There was some improvement in symptoms from before FMT, but bloating and discomfort remained.

 

Intestinal flora balance Comparative data

 

Evaluation and Discussion

Transplant Evaluation : Mild improvement of symptoms (improvement of constipation)
Adverse events: No Nothing

 

Transplant Evaluation :
FMT for irritable bowel syndrome (IBS) gas type and small intestinal bacterial overgrowth (SIBO). Slightly less gas; some improvement from pre-FMT, but still bloating and discomfort.

 

… and upwards

Articles about other Intestinal flora transplantation and case studies

November 03, 2025 Atopy/AllergyAutism Spectrum DisorderconstipationFecal Microflora Transplantationirritable bowel syndromeOther Diseasestrack recordulcerative colitis

Fecal microbiota transplantation results *As of September , 2025

The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others

November 02, 2024 Autism Spectrum DisorderLuke's Ashiya Clinic

12-year-old girl with autism spectrum disorder -Fecal microbiota transplant case report

Case presentation 12-year-old girl with autistic spectrum disorder summary A case of transplantation for autistic spectrum disorder. Improvement in bowel movements, sleep quality, and tantrums were observed, but not much change was seen in the hyperactivity aspect or impulsivity. Basic Information Patients :12-year-old girlAttending physician :Luke’s Ashiya ClinicMedical institution in charge of transplantation :Luke’s Ashiya […]

November 02, 2024 Autism Spectrum DisorderLuke's Ashiya Clinic

6-year-old boy with autism spectrum disorder -Fecal microbiota transplant case report

Case presentation 6-year-old boy with autistic spectrum disorder summary A case of transplantation for autism spectrum disorder (ASD). The patient has difficulty in understanding his surroundings and tends to be hyperactive. The main complaint was lack of concentration. No significant change was observed after transplantation. Basic Information Patients :6 year old boyAttending physician :Luke’s Ashiya […]