Female in her 60s, irritable bowel syndrome, atopy/allergy – fecal microbiota transplant case report
Case presentation 60s female, irritable bowel syndrome, atopy/allergy
summary
She has had persistent abdominal pain and diarrhea for more than 10 years, and her symptoms were exacerbated by anxiety and psychological stress. She also had food allergies and had a history of anaphylaxis.
After six transplants, diarrhea and abdominal pain almost disappeared. As for allergic symptoms, he no longer develops obvious urticaria, although he has had occasional itching. She has experienced an anaphylactic attack in the past, and her mental instability due to the anticipatory anxiety persists.
Basic Information
| Patients : | Woman in her 60s |
| Attending physician : | Medical Corporation Keimeikai Kimura Hospital |
| Medical institution in charge of transplantation : | Medical Corporation Keimeikai Kimura Hospital |
Information at the time of initial medical examination
| Disease name : | Irritable bowel syndrome, atopy/allergy |
| Time of onset : | About 10 years ago |
| Transplant Purpose: To | Improvement of disease and constitution |
| Chief complaint : | Has been allergic for some time. He gets urticaria from garlic, crab, fruit, alcohol, etc. When allergic symptoms occur, his blood pressure may drop and he often has diarrhea. He sometimes requires hospitalization. This year, he took steroids, and his symptoms lessened. |
| Medical history : | None noted |
| Background, family history, lifestyle, supplement use, etc : | Oral steroids, gastrointestinal drugs |
Transplant Information
| Transplantation period: from | 2020/9/8~2020/10/30 |
| Number of transplants : | 6 times |
| Change from first transplant to end of transplant : |
| 【1st transplantation questionnaire】 (From patient) I don’t feel well. Taking a bowel preparation and having normal stools. Discomfort in left lower abdomen but no obvious tenderness, bowel sounds normal. 【2nd transplantation questionnaire】 (From patient) No diarrhea. Appetite is good. No obvious tenderness in the abdomen, bowel sounds normal. 【3rd transplantation questionnaire】 (From patient) I have had diarrhea twice, but it seems to be less than before. No abdominal tenderness, bowel sounds normal. 【4th transplantation questionnaire】 (From patient) No diarrhea. Sometimes constipation. No abdominal tenderness. 【5th transplantation questionnaire】 (From patient) No diarrhea; once had no bowel movement for 2 days. 【6th transplantation questionnaire】 (From patient) No abdominal pain, daily bowel movements. (Interview 3 months after transplantation) Occasional diarrhea, but not as severe as before the transplant. Skin rashes continue to appear, so steroid ointment is applied. No abdominal tenderness, bowel sounds normal. |
Intestinal flora balance Comparative data
| (From the questionnaire): How did your symptoms of concern change after the transplant? We would appreciate it if you could describe in as much detail as possible, including your physical and mental condition before, during, and after the transplant. |
| I am not too sure yet, but I have been told that my complexion has improved, and I have not had a single bout of diarrhea since April. |
Evaluation and Discussion
| Transplant Evaluation : | Moderate improvement of symptoms |
| Adverse events: No | Nothing |
| Changes after completion of transplant : | diarrhea symptom relieved |
| Transplant General Comments and Discussion : |
| Abdominal symptoms such as diarrhea and abdominal pain were transplantable. Allergic symptoms also showed improvement. |
… and upwards
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