Atopic dermatitis, 4-year-old boy -Fecal microflora transplantation case report
Case presentation: 4-year-old boy, atopic dermatitis (under observation)
summary
She had food sensitivity and itchy, dry skin all over her body. After the transplant, the itching became worse for a while, but after the sixth and final transplant, the degree of itching improved, and at the time of the eighth transplant, she did not scratch her body at the examination, and the skin rash became less severe.
It is hoped that the restoration of lactobacilli will improve the mitochondrial function by repairing the intestinal wall and improving the intestinal environment, leading to an improvement in hypersensitivity.
Basic Information
| Patients : | 4 years old, boy |
| Attending physician : | Haruna Clinic |
| Medical institution in charge of transplantation : | Haruna Clinic |
Information at the time of initial medical examination
| Disease name : | Atopic dermatitis, food sensitivities |
| Time of onset : | 0 year old |
| Transplant Purpose: To | Allergies (target; most foods) skin problem Other (atopic dermatitis, food sensitivities) |
| Chief complaint : | Eczema, itching, food sensitivities |
| Medications being taken : | Nothing |
| Medical history : | epilepsy |
| Background, family history, lifestyle, supplement use, etc : | ALVEX, LACTIC ACID BACTERIA, VITAMIN D |
Transplant Information
| Transplantation period: from | May 25, 2019 – September 28, 2019 |
| Number of transplants : | 8 times |
| Change from first transplant to end of transplant : |
|
There was no change until the 6th session, but after the 7th session, the skin peeled off and the itching calmed down somewhat. However, the food sensitivity has not changed. 【1st transplantation questionnaire】 |
| Changes after completion of transplant : |
| Slightly more itchy |
Evaluation and Discussion
| Transplant Evaluation : | Mild improvement of symptoms |
| Pre- and post-transplant flora balance test changes : | awaiting test results |
| Blood test changes : |
Eosinophils and IgE are increasing |
| POMS2 SCORE CHANGE : | Not implemented |
＜Intestinal flora balance before transplant data＞
＜Intestinal flora balance Post-transplant data＞
awaiting results
| His/her experience (from the questionnaire) : |
| I didn’t really feel better, but after the 7th transplant, the itching seemed to be a little less. Food sensitivity has not changed. |
| Adverse events: No |
| Nothing |
| Transplant General Comments and Discussion : |
| The transplant has gradually improved the degree of atopy, but food sensitivities have not changed. He is considering additional transplants in the future while growing the transplanted fungal solution. |
… and upwards
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The number of actual fecal microbiota transplants by case in our study group is as follows Case reports by disease You can view case reports by disease from the links below: [Ulcerative Colitis]https://fmt-japan.org/research-activities/fmt-cases-index?tag=uc [Irritable Bowel Syndrome]https://fmt-japan.org/research-activities/fmt-cases-index?tag=ibs [Atopic Allergies]https://fmt-japan.org/research-activities/fmt-cases-index?tag=allergy [Constipation]https://fmt-japan.org/research-activities/fmt-cases-index?tag=constipation [ASD (Autism Spectrum Disorder)]https://fmt-japan.org/research-activities/fmt-cases-index?tag=asd [Other Diseases]https://fmt-japan.org/research-activities/fmt-cases-index?tag=others
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