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Intestinal flora transplantation and case studies

Atopic dermatitis, 4-year-old boy -Fecal microflora transplantation case report

Case presentation: 4-year-old boy, atopic dermatitis (under observation)

summary

She had food sensitivity and itchy, dry skin all over her body. After the transplant, the itching became worse for a while, but after the sixth and final transplant, the degree of itching improved, and at the time of the eighth transplant, she did not scratch her body at the examination, and the skin rash became less severe.
It is hoped that the restoration of lactobacilli will improve the mitochondrial function by repairing the intestinal wall and improving the intestinal environment, leading to an improvement in hypersensitivity.

Basic Information

Patients : 4 years old, boy
Attending physician : Haruna Clinic
Medical institution in charge of transplantation : Haruna Clinic

Information at the time of initial medical examination

Disease name : Atopic dermatitis, food sensitivities
Time of onset : 0 year old
Transplant Purpose: To Allergies (target; most foods)
skin problem
Other (atopic dermatitis, food sensitivities)
Chief complaint : Eczema, itching, food sensitivities
Medications being taken : Nothing
Medical history : epilepsy
Background, family history, lifestyle, supplement use, etc : ALVEX, LACTIC ACID BACTERIA, VITAMIN D

Transplant Information

Transplantation period: from May 25, 2019 – September 28, 2019
Number of transplants : 8 times
Change from first transplant to end of transplant :

There was no change until the 6th session, but after the 7th session, the skin peeled off and the itching calmed down somewhat. However, the food sensitivity has not changed.

【1st transplantation questionnaire】
Atopic eczema and itching all over her body, but she is in a good mood.
I hope that the sensitivity will be removed by transplantation.
【2nd transplantation questionnaire】
Itching became stronger for 2 days from the day after transplant and she could not sleep.
The color and hardness of his stools are improving.
【3rd transplantation questionnaire】
Itching has become severe and she sometimes has trouble sleeping due to itching.
The skin is scattered with erythema all over.
【4th transplantation questionnaire】
Itching and skin condition remain the same.
【5th transplantation questionnaire】
He was constantly scratching himself during the examination, although it is getting better little by little.
【6th transplantation questionnaire】
The condition of the skin remains the same, with scattered dry skin rashes. He was constantly scratching his face and head.
The patient’s irritability has not changed, but she feels that it is getting worse and worse.
【7th transplantation questionnaire】
Shortly after the 6th transplant, she had a severe gastrointestinal cold.
The skin condition improved a little, but the intestinal sensitivity remained the same.
The itchiness improved a little and he was able to sleep.
【8th transplantation questionnaire】
The degree of itching has improved.
The dryness of the skin has also improved, and the number of clean areas has increased.
However, he is still applying steroids.
Changes after completion of transplant :
Slightly more itchy

Evaluation and Discussion

Transplant Evaluation : Mild improvement of symptoms
Pre- and post-transplant flora balance test changes : awaiting test results
Blood test changes :

Eosinophils and IgE are increasing
Zinc and copper are becoming more balanced
POMS2 SCORE CHANGE : Not implemented

＜Intestinal flora balance before transplant data＞

＜Intestinal flora balance Post-transplant data＞

awaiting results

His/her experience (from the questionnaire) :
I didn’t really feel better, but after the 7th transplant, the itching seemed to be a little less. Food sensitivity has not changed.
Adverse events: No
Nothing
Transplant General Comments and Discussion :
The transplant has gradually improved the degree of atopy, but food sensitivities have not changed. He is considering additional transplants in the future while growing the transplanted fungal solution.

… and upwards

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