Intestinal flora transplantation and case studies

Irritable bowel syndrome in a man in his 50’s – Case report of fecal microbiota transplantation

Case presentation: Male in his 50s, irritable bowel syndrome (under observation)

summary

IBS SYMPTOMS APPEARED ABOUT 20 YEARS AGO, DIARRHEA WAS THE MAIN SYMPTOM, ABOUT 20 TIMES A DAY AT MOST, AND THE SYMPTOMS WORSENED DUE TO WORK STRESS, ETC. IN 2012, HE RETIRED AND BECAME SELF-EMPLOYED, AND THE STRESS WAS REDUCED, BUT THE SYMPTOMS CONTINUED. 2014, HE HAD A DESCENDING COLON RESECTION DUE TO DIVERTICULITIS OF THE COLON, AT WHICH TIME HE TOOK ABS MEDICATION, AND HIS IBS SYMPTOMS WERE ALLEVIATED. IBS SYMPTOMS DECREASED AND DIARRHEA HAS DECREASED TO 4-5 TIMES A DAY. CURRENTLY TAKING IRIBO. VISITED OUR OUTPATIENT CLINIC ON OCTOBER 31, 2019 AND UNDERWENT 3 INTESTINAL FLORA TRANSPLANTATION SESSIONS FROM NOVEMBER 18, 2019. PATIENT IS UNDER OBSERVATION.

Basic Information

Patients : 50s Male
Attending physician : Medical Corporation Sakurashinkai Sante Clinic
Medical institution in charge of transplantation : Medical Corporation Sakurashinkai Sante Clinic

Information at the time of initial medical examination

Disease name : irritable bowel syndrome
At onset : About 20 years ago
Transplant Purpose: To Diarrhea, frequent gas
Chief complaint : diarrhea symptom
Medications being taken : man who allegedly pursues a career at the expense of love, feminine interests, etc.
Medical history : 2014 Descending colon resection due to diverticulitis of the colon
Background, family history, lifestyle, supplement use, etc : Patient has been treated at a local doctor since 1994 No use of supplements Consume a lot of vegetables

Transplant Information

Transplantation period: from November 18, 2019 – November 22, 2019
Number of transplants : 3 times
Change from first transplant to end of transplant :
Decrease in frequency of diarrhea Reduction in early postprandial bowel movements Decrease in gas emissions 【1st transplantation questionnaire】 2 stools/day. There were signs of nervousness. 【2nd transplantation questionnaire】 Stool frequency: 2 times/day. No abdominal symptoms. 【3rd transplantation questionnaire】 Gas was steadily decreasing, she was no longer going to the toilet immediately after meals, and the frequency of stools itself was also decreasing.
Changes after completion of transplant :
Now following

Evaluation and Discussion

Transplant Evaluation : Mild improvement of symptoms
Pre- and post-transplant flora balance test changes : under inspection
Blood test changes : under inspection
POMS2 SCORE CHANGE : under inspection
<Intestinal flora balance before transplant data> <Intestinal flora balance Post-transplant data> Scheduled to be tested
His/her experience (from the questionnaire) :
Very satisfied with treatment Symptom improvement still mild
Adverse events: No
Nothing
Transplant General Comments and Discussion :
After the second transplant, the frequency of diarrhea has decreased and he no longer has the urge to have a bowel movement within 30 minutes after a meal. She is now under less stress and is trying to lead a regular life and get enough sleep, so we can expect further improvement in her symptoms.
… and upwards
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